Section of Periodontology, Faculty of Odontology, University Complutense of Madrid, Madrid, Spain.
Faculty of Veterinary Lugo, University of Santiago de Compostela, Lugo, Spain.
Clin Oral Implants Res. 2018 Oct;29(10):986-995. doi: 10.1111/clr.13365. Epub 2018 Sep 23.
To study the hard and soft tissue volume after placing immediate (IMI) or delayed implants (DLI) with a triangular coronal macro-design (Test/T) or a conventional cylindrical design (Control/C).
T/C implants were inserted in healed ridges or in fresh extraction sockets of eight beagle dogs. Biopsies were processed for Micro-CT analysis and dental stone casts were optically scanned to obtain STL files revealing the soft tissue contours at 12 weeks. Image analysis software was utilized to match common landmarks superimposing the two sets of data. Three distinct volumes were calculated; buccal bone volume (B-BV), soft tissue volume below the implant shoulder (EC-STV), and the soft tissue volume above the implant shoulder (SC-STV). Using linear measurements, the soft tissue height (STH), the mucosal thickness (MT-IS), and the distance from the implant shoulder to the bone crest (I-BC) were assessed in the digital images and in conventional histology to assess the concordance, reproducibility, and reliability.
There were no significant differences between test and control implants regarding the buccal bone volume, although test implants had greater B-BV in all locations except for PM2. The soft tissue volume was similar at T/C implants. The surgical approach influenced the distribution of the total tissue volume. In the IMI, a low position of the bone crest was correlated with low values of B-BV, SC-STV, MT-IS, and STH. Linear measurements showed a high correlation between the histology and digital measurements and high inter and intra examiner agreement.
The superimposition of Micro-CT/STL allowed the analysis of soft and hard tissue volumes. Reduction of the implant buccal aspect resulted in nonsignificant higher bone volume although similar soft tissue volume while the surgical approach influenced soft tissue response.
研究采用三角形冠部宏观设计（测试/T）或传统圆柱形设计（对照/C）即刻（IMI）或延迟植入（DLI）后软硬组织体积的变化。
将 T/C 种植体植入 8 只比格犬的愈合牙槽嵴或新鲜拔牙窝中。对组织进行活检，用于 Micro-CT 分析，并对牙石模型进行光学扫描，以在 12 周时获得显示软组织轮廓的 STL 文件。使用图像分析软件匹配共同的标志点，将两组数据叠加。计算三个不同的体积：颊侧骨体积（B-BV）、种植体肩下的软组织体积（EC-STV）和种植体肩上的软组织体积（SC-STV）。通过线性测量，在数字图像和常规组织学中评估软组织高度（STH）、黏膜厚度（MT-IS）和种植体肩到骨嵴的距离（I-BC），以评估一致性、可重复性和可靠性。
在颊侧骨体积方面，测试和对照种植体之间没有显著差异，尽管除了 PM2 外，测试种植体在所有位置都有更大的 B-BV。T/C 种植体的软组织体积相似。手术方法影响了总组织体积的分布。在即刻植入中，骨嵴位置较低与 B-BV、SC-STV、MT-IS 和 STH 值较低相关。线性测量显示组织学和数字测量之间具有高度相关性，以及检查者之间和内部的高度一致性。
Micro-CT/STL 的叠加允许分析软硬组织体积。尽管软组织体积相似，但种植体颊侧的减少导致非显著更高的骨量，而手术方法影响软组织反应。
