来自兔抗血清与大鼠脑突触膜和胸腺细胞的体外交叉反应抗体。
In vitro cross-reacting antibodies from rabbit antisera to rat brain synaptic membranes and thymocytes.
作者信息
Janković B D, Horvat J, Mitrović K, Mostarica M
出版信息
Scand J Immunol. 1977;6(8):843-7. doi: 10.1111/j.1365-3083.1977.tb02159.x.
Rabbit anti-rat brain synaptic membrane and anti-rat thymocyte antisera were used in cytotoxicity, immunofluorescence, and absorption assays to define the antigenic relationship between the rat brain and thymocytes, and the localizing properties of antibodies. Both antisera cross-reacted with brain tissue and thymocytes. However, anti-synaptic membrane and anti-thymocyte antisera also contained antibodies specific for neurons and thymocytes, respectively. Immunofluorescence showed that antibodies from anti-thymocyte antiserum reacted with antigenic determinants situated on the surface membrane of brain cells.
兔抗大鼠脑突触膜抗血清和兔抗大鼠胸腺细胞抗血清被用于细胞毒性、免疫荧光和吸收试验，以确定大鼠脑和胸腺细胞之间的抗原关系以及抗体的定位特性。两种抗血清均与脑组织和胸腺细胞发生交叉反应。然而，抗突触膜抗血清和抗胸腺细胞抗血清也分别含有对神经元和胸腺细胞特异的抗体。免疫荧光显示，抗胸腺细胞抗血清中的抗体与位于脑细胞表面膜上的抗原决定簇发生反应。
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