Moriuchi T, Kasai M, Kobayashi H
Gan. 1979 Dec;70(6):825-8.
Immunization of rabbits with rat leukemia DBLA-6 resulted in the production of antisera which upon absorption with hepatoma cells were specific for rat immature T lymphocytes. The antisera showed cytotoxicity against thymocytes and killed 75 approximately 90% of them, whereas the antisera had no cytotoxic effect on peripheral lymphocytes from the spleen, lymph node, and bone marrow of rats. The antisera also showed cytotoxicity against rat lymphatic leukemia and lymphoma cells of all lines tested but not against rat myelogenous leukemia and erythroleukemia cells. The cytotoxic activity of anti-DBLA-6 serum was completely absorbed with rat brain or thymocytes.
用大鼠白血病DBLA - 6免疫家兔产生了抗血清，该抗血清经肝癌细胞吸收后对大鼠未成熟T淋巴细胞具有特异性。这些抗血清对胸腺细胞表现出细胞毒性，能杀死约75%至90%的胸腺细胞，而对大鼠脾脏、淋巴结和骨髓的外周淋巴细胞没有细胞毒性作用。该抗血清对所有测试的大鼠淋巴白血病和淋巴瘤细胞系也表现出细胞毒性，但对大鼠髓性白血病和红白血病细胞没有细胞毒性。抗DBLA - 6血清的细胞毒性活性可被大鼠脑或胸腺细胞完全吸收。
