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电刺激对实验性去神经大鼠肌肉的影响。

The effect of electrical stimulation on the experimentally denervated rat muscle.

作者信息

Schimrigk K, McLaughlin J, Grüninger W

出版信息

Scand J Rehabil Med. 1977;9(2):55-60.

PMID:302482
Abstract

The m. quadriceps of white rats was electrically stimulated after nerve crush and after nerve section. Electrically stimulated muscles showed fewer central nuclei and a greater number of necrotic single fibres. The demonstration of motor endplates could not give a reliable indication of the onset of reinnervation. The various results show the importance of the trophic influence of the nerve and raise the suspicion that electrical stimulation has a retarding effect on the atrophy but also on regeneration of the fibres. After 7 weeks the unstimulated muscles show a greater degree of regeneration than the stimulated ones.

摘要

在对白鼠的股四头肌进行神经挤压和神经切断后,对其进行电刺激。电刺激的肌肉显示出较少的中央核和较多的坏死单纤维。运动终板的显示并不能可靠地表明再支配的开始。各种结果表明神经营养影响的重要性,并引发了一种怀疑,即电刺激不仅对纤维萎缩有延缓作用,对纤维再生也有延缓作用。7周后,未受刺激的肌肉比受刺激的肌肉显示出更大程度的再生。

相似文献

1
The effect of electrical stimulation on the experimentally denervated rat muscle.电刺激对实验性去神经大鼠肌肉的影响。
Scand J Rehabil Med. 1977;9(2):55-60.
2
Acetylcholine sensitivity and fibrillation potentials in electrically stimulated crush-denervated rat skeletal muscle.电刺激挤压去神经大鼠骨骼肌的乙酰胆碱敏感性和纤颤电位
Arch Phys Med Rehabil. 1983 May;64(5):217-20.
3
Effect of electrostimulation on denervated muscle.电刺激对失神经肌肉的影响。
Clin Orthop Relat Res. 1992 Oct(283):296-301.
4
Recovery of long-term denervated human muscles induced by electrical stimulation.电刺激诱导长期失神经支配的人类肌肉恢复。
Muscle Nerve. 2005 Jan;31(1):98-101. doi: 10.1002/mus.20149.
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Electrical stimulation prior to delayed reinnervation does not enhance recovery in muscles of rats.延迟再支配之前进行电刺激并不能促进大鼠肌肉的恢复。
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Electrical stimulation of denervated muscles of rats maintains mass and force, but not recovery following grafting.对大鼠失神经支配的肌肉进行电刺激可维持其质量和力量,但移植后无法恢复。
Restor Neurol Neurosci. 2006;24(1):41-54.
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Functional electrical stimulation of denervated muscles: basic issues.失神经肌肉的功能性电刺激:基本问题
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Electrical stimulation of paralyzed vibrissal muscles reduces endplate reinnervation and does not promote motor recovery after facial nerve repair in rats.对瘫痪的触须肌进行电刺激可减少终板再支配,且不能促进大鼠面神经修复后的运动恢复。
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[Effect of electrical stimulation patterns on denervated musculature and regenerated nerves].[电刺激模式对失神经肌肉组织和再生神经的影响]
Fortschr Med. 1985 Nov 7;103(41):961-4.
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Denervation-related changes in acetylcholine receptor density and distribution in the rat flexor digitorum sublimis muscle.大鼠指浅屈肌中乙酰胆碱受体密度和分布的去神经相关变化。
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引用本文的文献

1
Late administration of high-frequency electrical stimulation increases nerve regeneration without aggravating neuropathic pain in a nerve crush injury.在神经挤压伤中,晚期给予高频电刺激可促进神经再生,且不会加重神经性疼痛。
BMC Neurosci. 2018 Jun 25;19(1):37. doi: 10.1186/s12868-018-0437-9.
2
Structural differentiation of skeletal muscle fibers in the absence of innervation in humans.人类骨骼肌纤维在无神经支配情况下的结构分化
Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19339-44. doi: 10.1073/pnas.0709061104. Epub 2007 Nov 27.
3
Effect of nerve stimulation on rat skeletal muscle. A study of plasma membrane.
神经刺激对大鼠骨骼肌的影响。质膜研究。
Experientia. 1985 Nov 15;41(11):1396-8. doi: 10.1007/BF01950002.