a Department of Dermatology, Venereology and Andrology, Faculty of Medicine , Sohag University , Sohag , Egypt.
b Department of Plastic Surgery, Faculty of Medicine , Sohag University , Sohag , Egypt.
J Dermatolog Treat. 2019 Aug;30(5):492-497. doi: 10.1080/09546634.2018.1528329. Epub 2018 Nov 28.
Vitiligo is an acquired disfiguring common depigmented skin disease. This study aimed to compare the clinical efficacy and safety of suction blistering graft, mini punch and hair follicle techniques in treatment of patients with stable vitiligo. Thirty patients with stable vitiligo were included. Patients were divided into 3 groups, in group (A) 10 patient underwent suction blistering technique, in group (B) 10 patients underwent mini punch technique and in group (C) 10 patients underwent hair follicle technique. Then all patients in the three techniques were subjected to narrow-band ultraviolet B (NB-UVB) phototherapy for 3 months. All patients were assessed by determining the percentage of repigmentation and Dermatology Life Quality Index (DLQI) before and 3 months after the operation. The percentage of repigmentation of vitiligo in suction blister technique was significantly higher than both mini punch and hair follicle techniques ( value .001 and .0001 respectively). There was a statistically significant difference between the three techniques regarding DLQI score after operation ( value = .0001). This study concluded that suction blistering technique is more effective and safe than mini punch technique and hair follicle technique in treatment of stable vitiligo.
白癜风是一种获得性的、常见的、影响容貌的色素脱失性皮肤病。本研究旨在比较吸疱移植术、微型打孔术和毛囊单位移植术治疗稳定期白癜风的临床疗效和安全性。选取 30 例稳定期白癜风患者，分为 A、B、C 三组，A 组 10 例患者行吸疱移植术，B 组 10 例患者行微型打孔术，C 组 10 例患者行毛囊单位移植术。三组患者均在术后 3 个月内行窄谱中波紫外线（NB-UVB）光疗。分别于治疗前、治疗 3 个月后，通过评估患者的色素恢复比例和皮肤病生活质量指数（DLQI）评估疗效。吸疱移植术组的白癜风色素恢复比例明显高于微型打孔术组和毛囊单位移植术组（ value.001 和.0001）。三组患者术后的 DLQI 评分有统计学差异（ value = .0001）。研究表明，与微型打孔术和毛囊单位移植术相比，吸疱移植术治疗稳定期白癜风更有效、更安全。
