Dermatology and Venereology, Faculty of Medicine, Zagazig university, Zagazig, Egypt.
Arch Dermatol Res. 2024 Jun 8;316(7):358. doi: 10.1007/s00403-024-03045-6.
Follicular cell suspension (FCS) transplantation is a novel surgical method for treating resistant stable vitiligo, whereas mini punch grafting is an established effective method for treating stable vitiligo. The combination of FCS and mini punch grafting is a better strategy for the treatment of resistant stable vitiligo. The aim of the study was to evaluate the efficacy of follicular cell suspension, mini punch grafting, and a combination of both techniques in the treatment of stable vitiligo. This prospective comparative study was conducted on 48 patients with stable vitiligo. They were divided into three equal groups, including group A (treated with follicular cell suspension), group B (treated with mini punch grafting), and group C (treated with the combination of both techniques). All patients were followed-up for six months for the assessment of their therapeutic response regarding clinical outcomes. By comparing the data of the three studied groups, we found that the difference in the degree of re-pigmentation after one and three months of treatment was not significant. However, the progress of re-pigmentation was significantly different after six months of treatment among the three studied groups (P = 0.027). Specifically, re-pigmentation was significantly better in group C than in groups A and B (P = 0.037 and 0.017, respectively), but it was not significantly different between groups A and B.
毛囊细胞悬液（FCS）移植是治疗耐药性稳定型白癜风的一种新的手术方法，而迷你打孔移植术是治疗稳定型白癜风的一种已确立的有效方法。FCS 与迷你打孔移植术相结合是治疗耐药性稳定型白癜风的更好策略。本研究旨在评估毛囊细胞悬液、迷你打孔移植术以及两者联合技术治疗稳定型白癜风的疗效。这项前瞻性对照研究纳入了 48 例稳定型白癜风患者。他们被分为三组，包括 A 组（接受毛囊细胞悬液治疗）、B 组（接受迷你打孔移植术治疗）和 C 组（接受两种技术联合治疗）。所有患者均随访 6 个月，评估其临床疗效的治疗反应。通过比较三组研究数据，我们发现治疗后 1 个月和 3 个月时复色程度的差异无统计学意义。然而，治疗 6 个月后，三组之间的复色进展差异具有统计学意义（P=0.027）。具体而言，C 组的复色明显优于 A 组和 B 组（P=0.037 和 0.017），但 A 组和 B 组之间无显著差异。
