a Department of Otolaryngology-Head and Neck Surgery, University of Kansas School of Medicine , Kansas City , KS, USA.
b Department of Pediatrics, Adolescent Medicine, Indiana University School of Medicine , Indianapolis , IN, USA.
Hum Vaccin Immunother. 2019;15(7-8):1929-1934. doi: 10.1080/21645515.2018.1526559. Epub 2018 Nov 5.
As Otolaryngologists we have witnessed a rise in a new disease with human papilloma virus (HPV) associated oropharyngeal squamous cell carcinoma (OPSCC). As of 2018, HPV associated OPSCC has surpassed the incidence of HPV associated cervical cancer within the United States. Non-HPV related head and neck cancer is largely a preventable disease through avoidance of various environmental factors, and we have seen a significant decline in cancer rates through anti-tobacco campaigns and other public health efforts. Given the success of HPV vaccination campaigns and reduction in HPV associated cervical and other anogenital cancers, some would argue HPV OPSCC is largely a preventable disease through vaccination as well. The question remains is how do we as otolaryngologist, non-primary care providers yet surgeons for this disease, help to promote public health efforts to reduce HPV related OPSCC. Within this article, we discuss preliminary data that supports HPV vaccination with HPV related OPSCC and the ongoing needs by our profession to help support public efforts in reducing the burden of this HPV related cancer.
作为耳鼻喉科医生，我们已经见证了一种新疾病的出现，即与人乳头瘤病毒（HPV）相关的口咽鳞状细胞癌（OPSCC）。截至 2018 年，HPV 相关的 OPSCC 在发病率上已超过了美国的 HPV 相关宫颈癌。非 HPV 相关的头颈部癌症在很大程度上是可以通过避免各种环境因素来预防的疾病，我们已经通过反烟草运动和其他公共卫生努力看到癌症发病率的显著下降。鉴于 HPV 疫苗接种运动的成功以及 HPV 相关的宫颈癌和其他肛门生殖器癌症的减少，有人认为 HPV OPSCC 通过疫苗接种也在很大程度上是可以预防的疾病。问题仍然是，作为耳鼻喉科医生，我们作为非初级保健提供者但又是该疾病的外科医生，如何帮助促进公共卫生努力来减少 HPV 相关的 OPSCC。在本文中，我们讨论了支持 HPV 疫苗接种与 HPV 相关的 OPSCC 的初步数据，以及我们这一专业领域为帮助支持减少这种 HPV 相关癌症负担而持续存在的需求。
