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[麦角钙化醇在锶佝偻病中的毒性作用]

[Toxic action of ergocalciferol in strontium rickets].

作者信息

Petrova E A, Miloserdova A G, Babaskina L I

出版信息

Vopr Pitan. 1977 Mar-Apr(2):41-3.

PMID:302527
Abstract

Tests conducted on albino rats of the Wistar line demonstrated that introduction of large doses of ergocalciferol (vitamin D2) to animals kept on a strontium-rich diet exhibiting signs of rickets brings about the development in them of specific manifestations of the D-vitamin activity, viz. rising level of calcium, strontium and inorganic phosphorus in the blood serum, lowering of the alkaline phosphatase activity and a greater degree of the soft tissues calcification.

摘要

对Wistar品系的白化大鼠进行的试验表明,给食用富含锶且有佝偻病症状的饮食的动物大剂量引入麦角钙化醇(维生素D2),会使它们出现维生素D活性的特定表现,即血清中钙、锶和无机磷水平升高,碱性磷酸酶活性降低,以及软组织钙化程度更高。

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