Binns M M, Boursnell M E, Tomley F M, Brown D K
J Gen Virol. 1986 Dec;67 ( Pt 12):2825-31. doi: 10.1099/0022-1317-67-12-2825.
The nucleotide sequences of the spike precursor genes of infectious bronchitis virus strains M41 and 6/82 have been determined and compared with that of the Beaudette strain which we have previously sequenced. The two Massachusetts strains, M41 and Beaudette, were found to be remarkably similar, having only 3.7% of the amino acids different. The situation with 6/82, one of the new field isolates, is quite different and this strain had 13.8% of its amino acids different from Beaudette. The differences identified are discussed in terms of the structural features of the spike protein.
已测定传染性支气管炎病毒株M41和6/82的刺突前体基因的核苷酸序列，并与我们之前测序的Beaudette株进行了比较。发现两株马萨诸塞州毒株M41和Beaudette非常相似，只有3.7%的氨基酸不同。新的现场分离株之一6/82的情况则大不相同，该毒株有13.8%的氨基酸与Beaudette不同。根据刺突蛋白的结构特征对所发现的差异进行了讨论。
