Harati Y, Niakan E
J Neurol Neurosurg Psychiatry. 1986 Nov;49(11):1313-6. doi: 10.1136/jnnp.49.11.1313.
Thirty-three patients with inflammatory-angiopathic neuropathy diagnosed by sural nerve biopsy, were investigated to determine the underlying disease. Twenty-six patients had symmetrical sensorimotor polyneuropathy and seven had mononeuropathy multiplex. An aetiology for inflammatory-angiopathic neuropathy was found in only eight patients: typical collagen vascular disease in five and malignant tumour in three. Sixteen patients received prednisone and/or immunosuppressive drug therapy and 12 (75%) responded to treatment. This study demonstrates that typical collagen vascular diseases are not the most common cause of inflammatory-angiopathic neuropathy, that symmetrical polyneuropathy is seen in 75.8% of inflammatory-angiopathic neuropathy patients. Prednisone and/or immunosuppressive agents appear effective regardless of aetiology.
对33例经腓肠神经活检诊断为炎性血管病性神经病的患者进行了调查，以确定其潜在疾病。26例患者患有对称性感觉运动性多发性神经病，7例患有多灶性单神经病。仅在8例患者中发现了炎性血管病性神经病的病因：5例为典型的胶原血管病，3例为恶性肿瘤。16例患者接受了泼尼松和/或免疫抑制药物治疗，其中12例（75%）对治疗有反应。本研究表明，典型的胶原血管病并非炎性血管病性神经病的最常见病因，75.8%的炎性血管病性神经病患者表现为对称性多发性神经病。无论病因如何，泼尼松和/或免疫抑制剂似乎都有效。
