Kusumoto S, Koga K, Tsukino H, Nagamachi S, Nishikawa K, Watanabe K
Jpn J Clin Oncol. 1986 Dec;16(4):319-23.
Results of radiotherapy for lung cancer in the elderly were compared with those in younger patients. A total of 129 patients were treated by radiation therapy with or without chemotherapy. Fifty-six patients (43.4%) were 70 years old or more (elderly group) at the time of treatment, and the remaining 73 patients were below age 70 (younger group). Treatment results in the elderly group were nearly the same as those in the younger group in all stages of the disease. Survival time was longer for patients with performance status (PS) of 0 to 2 than for those with PS 3 or 4 regardless of age (p less than 0.05). The survival time of the elderly group was nearly the same as that of the younger group for squamous cell carcinoma, but somewhat shorter for adenocarcinoma although the difference was not statistically significant. There was no difference in survival between the two groups when they were treated by combined radiation therapy and chemotherapy. Our results suggest that elderly patients can be treated as safely as younger patients by radiotherapy alone or combined radiation therapy and chemotherapy.
对老年肺癌患者的放射治疗结果与年轻患者的结果进行了比较。共有129例患者接受了单纯放疗或放化疗。56例患者(43.4%)在治疗时年龄为70岁及以上(老年组),其余73例患者年龄在70岁以下(年轻组)。在疾病的所有阶段,老年组的治疗结果与年轻组几乎相同。无论年龄大小,体能状态(PS)为0至2的患者生存时间比PS为3或4的患者长(p<0.05)。鳞状细胞癌老年组的生存时间与年轻组几乎相同,但腺癌老年组的生存时间略短,尽管差异无统计学意义。两组接受联合放化疗时生存无差异。我们的结果表明,老年患者接受单纯放疗或联合放化疗与年轻患者一样安全。