Ⅲ期肺癌术后放疗的意义
Significance of postoperative irradiation for stage III lung cancer.
作者信息
Nishikawa K, Koga K, Shibata K, Wake N, Takeuchi M, Watanabe K
出版信息
Radiat Med. 1984 Apr-Jun;2(2):143-7.
The significance of postoperative irradiation for stage III lung cancer was analyzed in 30 patients. Radiation was given to 15 of the patients and the remaining 15 did not receive any radiation therapy following surgical intervention. A total dose of 40 to 70 Gy was given to the radiation group with a fraction dose of 2 Gy five times a week using cobalt 60 gamma-ray or linac 10 MV X-ray. There was no significant difference of survival time between these two groups. However, in analyzing modes of operation, radiation seemed to improve the survival rate in patients who underwent curative or relatively curative operations (P = 0.1), while the patients who underwent non-curative operations did not receive any benefit from the postoperative irradiation. Some reasons for the ineffectiveness in cases of non-curative operation are discussed.
对30例Ⅲ期肺癌患者术后放疗的意义进行了分析。15例患者接受了放疗，其余15例在手术干预后未接受任何放疗。放疗组给予的总剂量为40至70Gy，采用钴60γ射线或直线加速器10MV X射线，每周5次，每次分割剂量为2Gy。两组患者的生存时间无显著差异。然而，在分析手术方式时，放疗似乎提高了接受根治性或相对根治性手术患者的生存率（P = 0.1），而接受非根治性手术的患者未从术后放疗中获益。讨论了非根治性手术病例无效的一些原因。
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