Department of Neurology, Huashan Hospital, Fudan University, No. 12, Wulumuqi Road (M), Jing'an District, Shanghai, 200040, People's Republic of China.
Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (originally Shanghai First People's Hospital), No. 100, Haining Road, Hongkou District, Shanghai, 200080, People's Republic of China.
J Neurol. 2018 Dec;265(12):2825-2833. doi: 10.1007/s00415-018-9062-x. Epub 2018 Sep 25.
Little is known about ping-pong gaze (PPG) outside of individual case reports. We aimed to describe PPG through an observational study and literature review.
Consecutive patients with PPG at Shanghai General Hospital (SGH) from February 2016 to March 2018 were enrolled. A literature review through March 2018 was conducted.
Of the 14 patients with PPG in SGH, the median age was 60 years and 12 were males. The median Glasgow coma scale score was 7.5. The cycle of the PPG ranged from 1.5 to 6.5 s. The leading three etiologies were acute ischemic stroke in five patients, post-seizure state in three patients, and hypoxic-ischemic encephalopathy in two patients. A total of 88.9% (8/9) of the patients with consistent whole-field PPG had similar bilateral hemispheric damage, whereas 80.0% (4/5) of the patients with PPG in the hemifield had unilateral or extremely asymmetric bilateral hemispheric damage. The hemifiled side was the same side as the sole/dominant hemispheric lesion. The final clinical outcomes were neurologic remission for seven patients, vegetative state for one patient, and death for six patients.
PPG is a sign with localizing value that suggests hemispheric damage and asymmetric PPG might help to predict lateralization of the lesions. Acute ischemic stroke is the most common cause of PPG. Etiology and initial outcome are likely important prognostic factors of PPG.
除了个别病例报告外，人们对乒乓球眼动（PPG）知之甚少。我们旨在通过观察性研究和文献回顾来描述 PPG。
连续纳入 2016 年 2 月至 2018 年 3 月在上海总医院（SGH）就诊的 PPG 患者。同时对截至 2018 年 3 月的文献进行回顾。
在 SGH 的 14 例 PPG 患者中，中位年龄为 60 岁，12 例为男性。中位格拉斯哥昏迷评分（GCS）为 7.5。PPG 的周期范围为 1.5 至 6.5 秒。主要病因有：5 例急性缺血性脑卒中、3 例癫痫发作后状态、2 例缺氧缺血性脑病。88.9%（8/9）具有一致全视野 PPG 的患者存在双侧半球相似损伤，而 80.0%（4/5）存在视野内 PPG 的患者存在单侧或极度不对称的双侧半球损伤。视野侧与单侧或极度不对称的病变侧半球相同。最终临床结局为 7 例患者神经功能缓解、1 例患者植物状态、6 例患者死亡。
PPG 是一种具有定位价值的体征，提示半球损伤，不对称 PPG 可能有助于预测病变的侧化。急性缺血性脑卒中是 PPG 最常见的病因。病因和初始结局可能是 PPG 的重要预后因素。
