Pempinello C, Haghighi P, Lee S, Curtis G P
Microsurgery. 1986;7(4):161-5. doi: 10.1002/micr.1920070407.
A total of 52 syngeneic heterotopic heart transplants were performed using 9-0 Dexon microsutures to see if these anastomoses could be tolerable when challenged by the burden of transplanted heart and lung. Eighteen long-term surviving transplants were verified by reliable ECG, Doppler tracings, and direct palpation of the heart grafts. Animals sacrificed at monthly intervals beginning 3 to 6 months posttransplantation were free of thrombus, lung abscesses, and separation at the anastomoses. Even though foreign body reaction was still present up to 5 months posttransplantation, no actual sutures were present after 3 months. From these observations, Dexon microsuture is acceptable in organ transplantation procedures.
共进行了52例同基因异位心脏移植，使用9-0 Dexon显微缝线，以观察当受到移植心肺负担的挑战时，这些吻合口是否能够耐受。通过可靠的心电图、多普勒描记图以及对心脏移植物的直接触诊，证实了18例长期存活的移植病例。从移植后3至6个月开始，每月处死的动物均未出现血栓、肺脓肿以及吻合口分离。尽管移植后5个月仍存在异物反应，但3个月后已无实际缝线。基于这些观察结果，Dexon显微缝线在器官移植手术中是可以接受的。
