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Re-evaluating the potential of immunoprophylaxis and/or immunotherapy for infections caused by multidrug resistant Klebsiella pneumoniae.

作者信息

Kobayashi Scott D, DeLeo Frank R

机构信息

Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, 59840, USA.

出版信息

Future Microbiol. 2018 Sep;13(12):1343-1346. doi: 10.2217/fmb-2018-0189. Epub 2018 Sep 26.

DOI:10.2217/fmb-2018-0189
PMID:30256152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6190217/
Abstract
摘要

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Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection.新型广谱抗碳青霉烯类耐药肺炎克雷伯菌荚膜抗体可预防感染。
mBio. 2018 Apr 3;9(2):e00091-18. doi: 10.1128/mBio.00091-18.
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mBio. 2018 Mar 13;9(2):e00297-18. doi: 10.1128/mBio.00297-18.
4
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Nat Commun. 2017 Dec 8;8(1):1991. doi: 10.1038/s41467-017-02223-7.
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Angew Chem Int Ed Engl. 2017 Nov 6;56(45):13973-13978. doi: 10.1002/anie.201700964. Epub 2017 Oct 5.
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Anti-LPS antibodies protect against Klebsiella pneumoniae by empowering neutrophil-mediated clearance without neutralizing TLR4.抗脂多糖抗体通过增强中性粒细胞介导的清除作用而不中和Toll样受体4来抵御肺炎克雷伯菌。
JCI Insight. 2017 May 4;2(9). doi: 10.1172/jci.insight.92774.
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Antimicrob Agents Chemother. 2017 Mar 24;61(4). doi: 10.1128/AAC.02610-16. Print 2017 Apr.
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