• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

与双膦酸盐治疗相关的非典型股骨骨折的手术治疗。

Surgical Management of Atypical Femur Fractures Associated With Bisphosphonate Therapy.

机构信息

From the Harborview Medical Center, Seattle, WA (Dr. Githens), the Penn State Deparment Orthopaedic Surgery, Pennsylvania State University, State College, PA (Dr. Garner), and the Harborview Medical Center, University of Washington, Seattle, WA (Dr. Firoozabadi).

出版信息

J Am Acad Orthop Surg. 2018 Dec 15;26(24):864-871. doi: 10.5435/JAAOS-D-16-00717.

DOI:10.5435/JAAOS-D-16-00717
PMID:30256339
Abstract

Atypical femur fractures associated with long-term bisphosphonate use can be challenging injuries to manage. Not only do they have a prolonged healing time and increased rate of nonunion as compared to typical femur fractures, intraoperative complications are not infrequent and can be catastrophic. Given the pathologic nature of these fractures, a multidisciplinary approach to the patient's care is necessary. Treatment begins with medical optimization and careful surgical planning. Radiographic characteristics of the fracture and femoral osteology dictate reduction strategy, adjunctive surgical techniques, and implant choice. Intraoperative complications including malreduction, iatrogenic fracture, and fracture propagation can be avoided with thoughtful planning. The purpose of this article is to discuss the technical aspects of surgical management of atypical femur fractures. We also discuss management of intraoperative complications and treatment failure. Finally, we provide an update on recommendations for postoperative medical treatment and management of the contralateral femur.

摘要

与长期使用双膦酸盐相关的非典型股骨骨折是一种具有挑战性的损伤,难以处理。与典型的股骨骨折相比,它们不仅愈合时间延长,且不愈合的发生率更高,术中并发症也不少见,甚至可能是灾难性的。鉴于这些骨折的病理性,需要对患者进行多学科治疗。治疗始于医疗优化和仔细的手术计划。骨折和股骨干骺端的影像学特征决定了复位策略、辅助手术技术和植入物的选择。通过周密的计划,可以避免术中并发症,如复位不良、医源性骨折和骨折扩展。本文的目的是讨论非典型股骨骨折的手术治疗的技术方面。我们还讨论了术中并发症和治疗失败的处理。最后,我们提供了关于术后药物治疗和对侧股骨处理的建议的最新信息。

相似文献

1
Surgical Management of Atypical Femur Fractures Associated With Bisphosphonate Therapy.与双膦酸盐治疗相关的非典型股骨骨折的手术治疗。
J Am Acad Orthop Surg. 2018 Dec 15;26(24):864-871. doi: 10.5435/JAAOS-D-16-00717.
2
Bilateral atypical femur fractures without bisphosphonate exposure.未使用双膦酸盐类药物的双侧非典型股骨骨折
Skeletal Radiol. 2017 Feb;46(2):241-247. doi: 10.1007/s00256-016-2526-0. Epub 2016 Nov 30.
3
Atypical femur fractures among breast cancer and multiple myeloma patients receiving intravenous bisphosphonate therapy.接受静脉用双膦酸盐治疗的乳腺癌和多发性骨髓瘤患者中的非典型股骨骨折。
Bone. 2012 Sep;51(3):524-7. doi: 10.1016/j.bone.2012.05.010. Epub 2012 May 23.
4
Treatment of femoral fracture nonunion after long-term bisphosphonate use.长期使用双膦酸盐后股骨骨折不愈合的治疗。
Orthopedics. 2012 Jun;35(6):e991-5. doi: 10.3928/01477447-20120525-51.
5
Factors Associated with Increased Healing Time in Complete Femoral Fractures After Long-Term Bisphosphonate Therapy.长期双膦酸盐治疗后股骨完全骨折愈合时间延长的相关因素。
J Bone Joint Surg Am. 2016 Dec 7;98(23):1978-1987. doi: 10.2106/JBJS.15.01422.
6
Atypical femoral fractures related to bisphosphonate treatment: issues and controversies related to their surgical management.与双膦酸盐治疗相关的非典型股骨骨折:与其手术治疗相关的问题与争议。
Bone Joint J. 2017 Mar;99-B(3):295-302. doi: 10.1302/0301-620X.99B3.BJJ-2016-0276.R2.
7
Surgical Complications Associated With Atypical Femur Fractures Attributed to Bisphosphonate Use.与双膦酸盐类药物使用所致非典型股骨骨折相关的手术并发症
J Surg Orthop Adv. 2018 Spring;27(1):14-20.
8
Surgical outcome of intramedullary nailing in patients with complete atypical femoral fracture: A multicenter retrospective study.完全性非典型股骨骨折患者髓内钉固定的手术结果:一项多中心回顾性研究。
Injury. 2017 Apr;48(4):941-945. doi: 10.1016/j.injury.2017.02.036. Epub 2017 Mar 1.
9
Long-term radiographic follow-up of bisphosphonate-associated atypical femur fractures.双膦酸盐相关非典型股骨骨折的长期影像学随访
Skeletal Radiol. 2016 May;45(5):627-33. doi: 10.1007/s00256-016-2346-2. Epub 2016 Feb 15.
10
Salvage of failed osteosynthesis for an atypical subtrochanteric femoral fracture associated with long-term bisphosphonate treatment using a 95° angled blade plate.采用 95°角度 blade 板对长期使用双膦酸盐治疗的伴发非典型转子下股骨折内固定失败进行补救。
Bone Joint J. 2018 Nov;100-B(11):1511-1517. doi: 10.1302/0301-620X.100B11.BJJ-2018-0306.R1.

引用本文的文献

1
Atypical Tibial Fracture Following Chronic Bisphosphonate Use: A Case Report and Review of the Literature.长期使用双膦酸盐后发生的非典型胫骨骨折:一例报告并文献复习
Cureus. 2024 Nov 6;16(11):e73165. doi: 10.7759/cureus.73165. eCollection 2024 Nov.
2
Surgical management and outcomes following atypical subtrochanteric femoral fractures - results from a matched-pair analysis of the registry for geriatric trauma of the German Trauma Society.非典型股骨转子下骨折的手术治疗及疗效分析——德国创伤学会老年创伤登记处的配对分析结果。
Arch Orthop Trauma Surg. 2024 Jun;144(6):2561-2572. doi: 10.1007/s00402-024-05297-3. Epub 2024 Apr 20.
3
Geriatric trauma: there is more to it than just the implant!
老年创伤:其内涵远不止植入物!
OTA Int. 2024 Mar 11;7(2 Suppl):e327. doi: 10.1097/OI9.0000000000000327. eCollection 2024 Mar.
4
Atypical femur fracture in a male without history of bisphosphonate use: a case report.男性非双膦酸盐使用史的非典型股骨骨折:病例报告。
J Med Case Rep. 2024 Jan 4;18(1):2. doi: 10.1186/s13256-023-04308-y.
5
Current concepts of bone grafting in trauma surgery.创伤外科中骨移植的当前概念。
J Clin Orthop Trauma. 2023 Aug 5;43:102231. doi: 10.1016/j.jcot.2023.102231. eCollection 2023 Aug.
6
Surgical strategy of the treatment of atypical femoral fractures.非典型股骨骨折的手术治疗策略
World J Orthop. 2023 May 18;14(5):302-311. doi: 10.5312/wjo.v14.i5.302.
7
Open Reduction and Internal Fixation of Simultaneous, Bilateral, Atypical Femoral Shaft Fractures After Nine Years of Bisphosphonate Treatment.双膦酸盐治疗九年后双侧非典型股骨干同时性骨折的切开复位内固定术
Cureus. 2021 Nov 1;13(11):e19177. doi: 10.7759/cureus.19177. eCollection 2021 Nov.
8
Current concepts in the management of bisphosphonate associated atypical femoral fractures.双膦酸盐相关非典型股骨骨折治疗的当前概念
World J Orthop. 2021 Sep 18;12(9):660-671. doi: 10.5312/wjo.v12.i9.660.
9
Atypical periprosthetic femoral fractures after arthroplasty for fracture are at high risk of complications.人工关节置换术后骨折的非典型假体周围股骨骨折并发症风险高。
Sci Rep. 2021 Jul 13;11(1):14378. doi: 10.1038/s41598-021-93574-1.
10
Atypical periprosthetic femoral fracture associated with long-term bisphosphonate therapy.与长期双膦酸盐治疗相关的非典型假体周围股骨骨折。
J Orthop Surg Res. 2020 Sep 15;15(1):414. doi: 10.1186/s13018-020-01941-x.