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非典型股骨转子下骨折的手术治疗及疗效分析——德国创伤学会老年创伤登记处的配对分析结果。

Surgical management and outcomes following atypical subtrochanteric femoral fractures - results from a matched-pair analysis of the registry for geriatric trauma of the German Trauma Society.

机构信息

Center for Orthopaedics and Trauma Surgery, University Hospital Marburg, 35043, Baldingerstrasse, Marburg, Germany.

Philipps University of Marburg, Marburg, Germany.

出版信息

Arch Orthop Trauma Surg. 2024 Jun;144(6):2561-2572. doi: 10.1007/s00402-024-05297-3. Epub 2024 Apr 20.

DOI:10.1007/s00402-024-05297-3
PMID:38642159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11211164/
Abstract

BACKGROUND AND OBJECTIVES

The outcomes of patients with atypical subtrochanteric fractures (ASFs) remain unclear. Data from a large international geriatric trauma registry were analysed to examine the outcome of patients with ASFs compared to patients with typical osteoporotic subtrochanteric fractures (TSFs).

MATERIALS AND METHODS

Data from the Registry for Geriatric Trauma of the German Trauma Society (Deutsche Gesellschaft für Unfallchirurgie [DGU]) (ATR-DGU) were analysed. All patients treated surgically for ASFs or TSFs were included in this analysis. Across both fracture types, a paired matching approach was conducted, where statistical twins were formed based on background characteristics sex, age, American Society of Anesthesiologists (ASA) score and walking ability. In-house mortality and mortality rates at the 120-day follow-up, as well as mobility at 7 and 120 days, the reoperation rate, hospital discharge management, the hospital readmission rate at the 120-day follow-up, health-related quality of life, type of surgical treatment and anti-osteoporotic therapy at 7 and 120 days, were assessed as outcome measures using a multivariate logistic regression analysis.

RESULTS

Amongst the 1,800 included patients, 1,781 had TSFs and 19 had ASFs. Logistic regression analysis revealed that patients with ASFs were more often treated with closed intramedullary nailing (RR = 3.59, p < 0.001) and had a higher probability of vitamin D supplementation as osteoporosis therapy at 120 days (RR = 0.88, p < 0.002). Patients with ASFs were also more likely to live at home after surgery (RR = 1.43, p < 0.001), and they also tended to continue living at home more often than patients with TSFs (RR = 1.33, p < 0.001). Accordingly, patients with TSFs had a higher relative risk of losing their self-sufficient living status, as indicated by increased rates of patients living at home preoperatively and being discharged to nursing homes (RR = 0.19, p < 0.001) or other hospitals (RR = 0.00, p < 0.001) postoperatively.

CONCLUSIONS

Surgical treatment of ASFs was marked by more frequent use of closed intramedullary fracture reduction. Furthermore, patients with ASFs were more likely to be discharged home and died significantly less often in the given timeframe. The rate of perioperative complications, as indicated by nonsignificant reoperation rates, as well as patient walking abilities during the follow-up period, remained unaffected.

摘要

背景与目的

非典型股骨转子下骨折(ASFs)患者的预后仍不清楚。本研究分析了来自一个大型国际老年创伤登记处的数据,以检查 ASFs 患者的预后与典型骨质疏松性转子下骨折(TSFs)患者的预后相比。

材料和方法

本研究分析了德国创伤学会(Deutsche Gesellschaft für Unfallchirurgie [DGU])老年创伤登记处(ATR-DGU)的数据。所有接受手术治疗的 ASFs 或 TSFs 患者均纳入本分析。在这两种骨折类型中,均采用配对匹配方法,根据背景特征(性别、年龄、美国麻醉医师协会 [ASA] 评分和行走能力)形成统计双胞胎。作为预后指标,采用多变量逻辑回归分析评估术后 7 天和 120 天的院内死亡率和死亡率、术后 7 天和 120 天的移动能力、再手术率、出院管理、术后 120 天的院内再入院率、健康相关生活质量、7 天和 120 天的手术治疗类型和抗骨质疏松治疗类型。

结果

在纳入的 1800 名患者中,1781 名患者患有 TSFs,19 名患者患有 ASFs。逻辑回归分析显示,ASFs 患者更常接受闭合髓内钉治疗(RR=3.59,p<0.001),并且在 120 天时更有可能接受维生素 D 补充作为骨质疏松症治疗(RR=0.88,p<0.002)。ASFs 患者术后更有可能在家中生活(RR=1.43,p<0.001),并且他们在家中生活的比例也高于 TSFs 患者(RR=1.33,p<0.001)。相应地,TSFs 患者失去自理生活状态的相对风险更高,这表现为术前在家中生活的患者和术后被安置在疗养院(RR=0.19,p<0.001)或其他医院(RR=0.00,p<0.001)的患者比例更高。

结论

ASFs 的手术治疗以更频繁地使用闭合髓内骨折复位为特征。此外,ASFs 患者出院回家的可能性更高,在给定的时间内死亡的可能性显著降低。手术并发症的发生率(通过无意义的再手术率表明)以及患者在随访期间的行走能力保持不变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7568/11211164/01c1730e9b85/402_2024_5297_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7568/11211164/cb3e99305b54/402_2024_5297_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7568/11211164/01c1730e9b85/402_2024_5297_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7568/11211164/cb3e99305b54/402_2024_5297_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7568/11211164/01c1730e9b85/402_2024_5297_Fig2_HTML.jpg

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Int J Surg Case Rep. 2023 Jul;108:108456. doi: 10.1016/j.ijscr.2023.108456. Epub 2023 Jul 3.
2
Incidence of Atypical Femoral Fractures in Patients on Osteoporosis Therapy-A Registry-Based Cohort Study.接受骨质疏松治疗患者非典型股骨骨折的发病率——一项基于登记处的队列研究
JBMR Plus. 2022 Sep 22;6(10):e10681. doi: 10.1002/jbm4.10681. eCollection 2022 Oct.
3
Health-related quality of life outcomes after surgical treatment of atypical femur fractures: a multicenter retrospective cohort study.
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JBMR Plus. 2021 Sep 30;5(11):e10514. doi: 10.1002/jbm4.10514. eCollection 2021 Nov.
4
Current concepts in the management of bisphosphonate associated atypical femoral fractures.双膦酸盐相关非典型股骨骨折治疗的当前概念
World J Orthop. 2021 Sep 18;12(9):660-671. doi: 10.5312/wjo.v12.i9.660.
5
Incidence of Atypical Femoral Fracture and Its Mortality in a Single Center in Singapore.新加坡某单一中心非典型股骨骨折的发病率及其死亡率
JBMR Plus. 2021 Jun 19;5(8):e10515. doi: 10.1002/jbm4.10515. eCollection 2021 Aug.
6
Incidence of atypical femoral fractures in the treatment of bone metastasis: An alert report.骨转移治疗中不典型股骨骨折的发生率:一份警示报告。
J Bone Oncol. 2020 Jun 20;23:100301. doi: 10.1016/j.jbo.2020.100301. eCollection 2020 Aug.
7
Atypical femoral fracture in patients with bone metastasis receiving denosumab therapy: a retrospective study and systematic review.接受地舒单抗治疗的骨转移患者的非典型股骨骨折:一项回顾性研究和系统评价。
BMC Cancer. 2019 Oct 22;19(1):980. doi: 10.1186/s12885-019-6236-6.
8
Outcomes for Elderly Patients With Atypical Femoral Fractures Compared to Typical Femoral Fractures for Length of Stay, Discharge Destination, and 30-Day Mortality Rate.老年非典型股骨骨折患者与典型股骨骨折患者在住院时间、出院去向及30天死亡率方面的结局比较。
Geriatr Orthop Surg Rehabil. 2018 Dec 26;9:2151459318820222. doi: 10.1177/2151459318820222. eCollection 2018.
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Surgical Management of Atypical Femur Fractures Associated With Bisphosphonate Therapy.与双膦酸盐治疗相关的非典型股骨骨折的手术治疗。
J Am Acad Orthop Surg. 2018 Dec 15;26(24):864-871. doi: 10.5435/JAAOS-D-16-00717.
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