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一种基于三嗪的新型π共轭介孔二维共价有机骨架:其体外抗癌活性。

A new triazine based π-conjugated mesoporous 2D covalent organic framework: its in vitro anticancer activities.

机构信息

Department of Materials Science, Indian Association for the Cultivation of Science Jadavpur, Kolkata - 700 032, India.

Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata - 700032, India.

出版信息

Chem Commun (Camb). 2018 Oct 9;54(81):11475-11478. doi: 10.1039/c8cc07289b.

Abstract

We report a new highly crystalline 2D π-conjugated hexagonal mesoporous covalent organic framework material, TrzCOF, through the solvothermal polycondensation of 1,3,5-tri(4-formylbiphenyl) benzene [Ph7(CHO)3, TFBPB] with 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TAPT) and it displayed excellent anticancer activity for human colorectal carcinoma HCT-116 cells.

摘要

我们报道了一种新型的高度结晶二维π共轭六方介孔共价有机骨架材料 TrzCOF,它是通过溶剂热缩聚 1,3,5-三(4-醛基联苯)[Ph7(CHO)3, TFBPB]与 2,4,6-三(4-氨基苯基)-1,3,5-三嗪(TAPT)得到的,并对人结肠癌细胞 HCT-116 显示出优异的抗癌活性。

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