Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706, USA.
Org Biomol Chem. 2018 Oct 10;16(39):7139-7142. doi: 10.1039/c8ob01773e.
Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens.
紫外线会导致皮肤癌。水杨酸和其他分子滤波器吸收破坏性辐射,但很容易被冲走。将其与胶原蛋白模拟肽结合,在反复洗涤后,仍能将水杨酸保留在含有胶原蛋白的皮肤替代品上。这种策略具有高度的模块性,可以提高防晒霜的耐水性。