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猫前脑中促肾上腺皮质激素免疫反应性神经元及其投射

ACTH-immunoreactive neurons and their projections in the cat forebrain.

作者信息

Kitahama K, Sallanon M, Buda C, Janin M, Dubois M P, Jouvet M

出版信息

Peptides. 1986 Sep-Oct;7(5):801-7. doi: 10.1016/0196-9781(86)90098-7.

DOI:10.1016/0196-9781(86)90098-7
PMID:3025823
Abstract

The organization of adrenocorticotropin (ACTH)-immunoreactive (IR) cell bodies and fibers in the cat forebrain is described. ACTH-IR cell bodies are found only in and around the arcuate nucleus of the hypothalamus (ARH). They are not detected elsewhere even after pretreatment with colchicine. ACTH-IR fibers are present in discrete areas of the hypothalamus, the septo-limbic areas and in the paraventricular thalamic nucleus. Complete electrolytic lesions of the ARH destroy ACTH-IR cell bodies as well as fibers in all parts of the brain. These results suggest that, in the cat forebrain, the ARH is the only source of ACTH-IR fibers.

摘要

本文描述了猫前脑促肾上腺皮质激素(ACTH)免疫反应性(IR)细胞体和纤维的组织分布。ACTH-IR细胞体仅在下丘脑弓状核(ARH)及其周围被发现。即使在用秋水仙碱预处理后,在其他部位也未检测到它们。ACTH-IR纤维存在于下丘脑的离散区域、隔-边缘区域以及丘脑室旁核。ARH的完全电解损伤会破坏脑内所有部位的ACTH-IR细胞体和纤维。这些结果表明,在猫前脑,ARH是ACTH-IR纤维的唯一来源。

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ACTH-immunoreactive neurons and their projections in the cat forebrain.猫前脑中促肾上腺皮质激素免疫反应性神经元及其投射
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