Toubeau G
C R Acad Hebd Seances Acad Sci D. 1978 Sep 18;287(5):499-502.
Immunoreactive neurons and fibers were localized in the Rat brain by immunocytochemistry using an anti-ACTH 17-39 antiserum. Neither adrenalectomy nor water deprivation affected intensity of distribution of reaction of labelled neurons whereas colchicine increased labelling of hypothalamic perikarya. These results support the neuronal origin of cerebral ACTH.
采用抗促肾上腺皮质激素17 - 39抗血清,通过免疫细胞化学方法在大鼠脑中定位免疫反应性神经元和纤维。肾上腺切除术和禁水均不影响标记神经元反应的分布强度,而秋水仙碱增加了下丘脑核周体的标记。这些结果支持大脑促肾上腺皮质激素的神经元起源。