Rahmoune Hakim, Boutrid Nada
Pediatrics Department, Setif University Hospital, Setif-1 University, Algeria.
Genetic & Nutritional Diseases Laboratory, Setif-1 University, Algeria.
Pediatr Neurol Briefs. 2018 Sep 14;32:9. doi: 10.15844/pedneurbriefs-32-9.
Investigators from different clinical and research centers from Paris, France studied the polymorphisms of the HLA class II loci in an autistic population. Through a case control design, they looked for the distribution of HLA class II alleles, genotypes and haplotypes in Autism Spectrum Disorders (ASD) patients meeting DSM-IV TR criteria versus healthy controls (HC).
来自法国巴黎不同临床和研究中心的研究人员对自闭症群体中人类白细胞抗原（HLA）II类基因座的多态性进行了研究。通过病例对照设计，他们探寻了符合《精神疾病诊断与统计手册》第四版修订版（DSM-IV TR）标准的自闭症谱系障碍（ASD）患者与健康对照者（HC）中HLA II类等位基因、基因型和单倍型的分布情况。
