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脊柱侧弯顶点的有限元应力研究

F.E.M. Stress-Investigation of Scolios Apex.

作者信息

Daghighi A, Tropp H, Dahlström N, Klarbring A

机构信息

Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.

Department of Clinical and Experimental Medicine & Division of Surgery Orthopedics and Oncology, Linköping University, 581 83 Linköping, Sweden.

出版信息

Open Biomed Eng J. 2018 Jul 31;12:51-71. doi: 10.2174/1874120701812010051. eCollection 2018.

Abstract

BACKGROUND

In scoliosis, kypholordos and wedge properties of the vertebrae should be involved in determining how stress is distributed in the vertebral column. The impact is logically expected to be maximal at the apex.

AIM

To introduce an algorithm for constructing artificial geometric models of the vertebral column from DICOM stacks, with the ultimate aim to obtain a formalized way to create simplistic models, which enhance and focus on wedge properties and relative tilting.

MATERIAL/METHODS: Our procedure requires parameter extraction from DICOM image-stacks (with PACS,IDS-7), mechanical FEM-modelling (with Matlab and Comsol). As a test implementation, models were constructed for five patients with thoracal idiopathic scoliosis with varying apex rotation. For a selection of load states, we calculated a response variable which is based upon distortion energy.

RESULTS

For the test implementation, pairwise t-tests show that our response variable is non-trivial and that it is chiefly sensitive to the transversal stresses (transversal stresses where of main interest to us, as opposed to the case of additional shear stresses, due to the lack of explicit surrounding tissue and ligaments in our model). Also, a pairwise t-test did not show a difference (n = 25, p-value≈0.084) between the cases of isotropic and orthotropic material modeling.

CONCLUSION

A step-by-step description is given for a procedure of constructing artificial geometric models from chest CT DICOM-stacks, such that the models are appropriate for semi-global stress-analysis, where the focus is on the wedge properties and relative tilting. The method is inappropriate for analyses where the local roughness and irregularities of surfaces are wanted features. A test application hints that one particular load state possibly has a high correlation to a certain response variable (based upon distortion energy distribution on a surface of the apex), however, the number of patients is too small to draw any statistical conclusions.

摘要

背景

在脊柱侧弯中,椎体的后凸-前凸和楔形特性应参与确定应力在脊柱中的分布方式。从逻辑上讲,这种影响在顶点处预计最大。

目的

引入一种从DICOM堆栈构建脊柱人工几何模型的算法,最终目的是获得一种形式化的方法来创建简化模型,该模型增强并关注楔形特性和相对倾斜度。

材料/方法:我们的程序需要从DICOM图像堆栈(使用PACS、IDS-7)中提取参数,进行机械有限元建模(使用Matlab和Comsol)。作为测试实现,为五名不同顶点旋转度的胸段特发性脊柱侧弯患者构建了模型。对于选定的载荷状态,我们计算了一个基于畸变能的响应变量。

结果

对于测试实现,成对t检验表明我们的响应变量并非无足轻重,并且它主要对横向应力敏感(横向应力是我们主要关注的,与额外剪应力的情况相反,因为我们的模型中缺乏明确的周围组织和韧带)。此外,成对t检验在各向同性和正交各向异性材料建模的情况之间未显示出差异(n = 25,p值≈0.084)。

结论

给出了从胸部CT DICOM堆栈构建人工几何模型的步骤描述,使得这些模型适用于半全局应力分析,重点是楔形特性和相对倾斜度。该方法不适用于需要表面局部粗糙度和不规则性的分析。一个测试应用表明,一种特定的载荷状态可能与某个响应变量(基于顶点表面的畸变能分布)有高度相关性,然而,患者数量太少,无法得出任何统计结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ada6/6128020/4bbf9c1739af/TOBEJ-12-51_F1.jpg

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