Liao Jin, Tian Xin, Wang Hao, Xiao Zheng
Neurology Department at Chongqing Medical University, Chongqing, China.
Neurology Department at the First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Street, Yuanjiagang, Yuzhong District, Chongqing, China.
Genes Dis. 2018 May 5;5(2):112-118. doi: 10.1016/j.gendis.2018.04.007. eCollection 2018 Jun.
Epilepsy and migraine often co-occur. From the clinical symptoms, they often have some signs of symptoms before onset; from the pathogenesis of epilepsy and migraine, both of them have a high degree of neuronal excitement and ion channel abnormalities; in terms of treatment, many antiepileptic drugs are work in migraine. All of this indicates that they interact with each other. But it is undeniable that there are interactions and relationships between them, and there are also some differences such as the different clinical episodes, the different ways of neuronal haperexcitability and the different drug treatment programs. And are they comorbidity? If we can better understand the correlation between seizures and migraines, then this will help develop better guidelines for clinical diagnosis and treatment.
癫痫和偏头痛常同时出现。从临床症状来看，它们在发作前往往有一些症状迹象；从癫痫和偏头痛的发病机制而言，二者都存在高度的神经元兴奋和离子通道异常；在治疗方面，许多抗癫痫药物对偏头痛有效。所有这些都表明它们相互影响。但不可否认的是，它们之间存在相互作用和关系，也存在一些差异，如临床发作不同、神经元过度兴奋的方式不同以及药物治疗方案不同。那么它们是共病吗？如果我们能更好地理解癫痫发作与偏头痛之间的关联，那么这将有助于制定更好的临床诊断和治疗指南。
