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生育期妇女健康问题的代际效应:对近期文献的综述。

Intergenerational Effects of Health Issues Among Women of Childbearing Age: a Review of the Recent Literature.

机构信息

Children's Nutrition Research Center, Baylor College of Medicine, 1100 Bates Street, Houston, TX, 77030, USA.

出版信息

Curr Nutr Rep. 2018 Dec;7(4):274-285. doi: 10.1007/s13668-018-0246-x.

Abstract

PURPOSE OF REVIEW

This review summarizes the latest scientific evidence, primarily from systematic reviews/meta-analyses and large cohort studies, on the impact of health issues among women of childbearing age and their effect on their offspring during pregnancy and from birth to adulthood.

RECENT FINDINGS

Women of childbearing age with overweight/obesity, diabetes, and hypertension prior to pregnancy are at increased risk for adverse outcomes during pregnancy, such as excessive gestational weight gain, gestational diabetes mellitus, and hypertensive disorders of pregnancy. These adverse outcomes could complicate delivery and put their offspring at risk of developing overweight/obesity, diabetes, and hypertension (i.e., intergenerational transmission of health issues). Interventions should target women of childbearing age, especially those who wish to conceive, in order to possibly stop the transmission of women's health issues to the offspring and favor a healthy pregnancy from the start. This could be one of the best strategies to promote both maternal and child health.

摘要

综述目的

本篇综述总结了最新的科学证据,主要来自系统评价/荟萃分析和大型队列研究,探讨了育龄妇女的健康问题及其对妊娠期间及其后代从出生到成年的影响。

最近的发现

妊娠前超重/肥胖、糖尿病和高血压的育龄妇女在妊娠期间发生不良结局的风险增加,例如过度的妊娠期体重增加、妊娠糖尿病和妊娠高血压疾病。这些不良结局可能会使分娩复杂化,并使她们的后代面临超重/肥胖、糖尿病和高血压的风险(即健康问题的代际传递)。干预措施应针对育龄妇女,特别是那些有生育意愿的妇女,以便可能阻止妇女健康问题向后代传递,并从一开始就促进健康妊娠。这可能是促进母婴健康的最佳策略之一。

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