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Peripheral artery disease in patients with diabetes: Epidemiology, mechanisms, and outcomes.糖尿病患者外周动脉疾病:流行病学、发病机制和结局。
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2
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BMC Surg. 2014 Oct 24;14:83. doi: 10.1186/1471-2482-14-83.
3
Peripheral arterial disease among adult diabetic patients attending a large outpatient diabetic clinic at a national referral hospital in Uganda: a descriptive cross sectional study.乌干达一家国家级转诊医院大型门诊糖尿病诊所成年糖尿病患者的外周动脉疾病:一项描述性横断面研究。
PLoS One. 2014 Aug 18;9(8):e105211. doi: 10.1371/journal.pone.0105211. eCollection 2014.
4
Metabolic syndrome for sub-Saharan Africans diabetes with peripheral arterial disease: a case-control study.撒哈拉以南非洲人代谢综合征合并外周动脉疾病与糖尿病:一项病例对照研究。
BMC Res Notes. 2014 Feb 24;7:104. doi: 10.1186/1756-0500-7-104.
5
Epidemiology and treatment outcomes of diabetic retinopathy in a diabetic population from Cameroon.喀麦隆糖尿病患者中糖尿病视网膜病变的流行病学和治疗结果。
BMC Ophthalmol. 2014 Feb 24;14:19. doi: 10.1186/1471-2415-14-19.
6
Use and utility of ankle brachial index in patients with diabetes.糖尿病患者踝臂指数的使用和效用。
Eur J Vasc Endovasc Surg. 2011 Jan;41(1):110-6. doi: 10.1016/j.ejvs.2010.09.020. Epub 2010 Nov 20.
7
Critical review of the ankle brachial index.踝肱指数的批判性综述。
Curr Cardiol Rev. 2008 May;4(2):101-6. doi: 10.2174/157340308784245810.
8
The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.预防动脉疾病和糖尿病进展(POPADAD)试验:糖尿病和无症状外周动脉疾病患者中阿司匹林和抗氧化剂的析因随机安慰剂对照试验。
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9
Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis.踝臂指数联合弗雷明汉风险评分预测心血管事件和死亡率:一项荟萃分析。
JAMA. 2008 Jul 9;300(2):197-208. doi: 10.1001/jama.300.2.197.
10
Sensitivity and specificity of ankle-brachial index for detecting angiographic stenosis of peripheral arteries.踝臂指数检测外周动脉血管造影狭窄的敏感性和特异性。
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踝肱压力指数在一组非洲裔黑人糖尿病患者中的应用。

The use of ankle brachial pressure indices in a cohort of black African diabetic patients.

作者信息

Weledji Elroy Patrick, Alemnju Neville Telelen, Nouediou Christophe

机构信息

Department of Surgery, Faculty of Health Sciences, University of Buea, Cameroon.

National Centre for Diabetes and Hypertension, Yaounde, Cameroon.

出版信息

Ann Med Surg (Lond). 2018 Sep 19;35:20-24. doi: 10.1016/j.amsu.2018.09.009. eCollection 2018 Nov.

DOI:10.1016/j.amsu.2018.09.009
PMID:30263113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6156742/
Abstract

BACKGROUND

Peripheral arterial disease is very common in patients with diabetes, but it remains grossly under-recognized in this type of patients. Ankle brachial index (ABI) is a simple, non-invasive and reproducible method for detection and improving risk stratification. However, the sensitivity appears to be lower in diabetic patients and, false 'high' readings occur because of the arterial calcification of the vessel media which render the vessels incompressible.

MATERIALS AND METHODS

The study evaluated the prevalence of a low ABI <0.9 in diabetic patients in a hospital-based cross sectional observational study. The study has been registered.

RESULTS

The prevalence of peripheral arterial disease in diabetics with ABI< 0.9 was 18%. The majority (77%) of responders were asymptomatic with mild PAD (ABI 0.7-0.9). Age >60 years, hypertension (systolic BP > 140 mmHg) and presence of foot ulcer were identified as independent risk factors. 22 participants (4.4%) of the 500 had ABI greater than 1.3 but were excluded in the analysis.

CONCLUSION

The prevalence of PAD in diabetics measured by the ABI index was low and the majority in our setting had mild PAD and were asymptomatic. ABI could be used in patients with diabetes, but values should be interpreted with precision, according to the clinical situation as higher values are common.

摘要

背景

外周动脉疾病在糖尿病患者中非常常见,但在这类患者中仍未得到充分认识。踝臂指数(ABI)是一种简单、无创且可重复的检测方法,有助于改善风险分层。然而,糖尿病患者中ABI的敏感性似乎较低,并且由于血管中层的动脉钙化导致血管不可压缩,会出现假性“高”读数。

材料与方法

在一项基于医院的横断面观察性研究中,评估糖尿病患者中ABI<0.9的患病率。该研究已注册。

结果

ABI<0.9的糖尿病患者外周动脉疾病患病率为18%。大多数(77%)有反应者无症状,患有轻度外周动脉疾病(ABI 0.7 - 0.9)。年龄>60岁、高血压(收缩压>140 mmHg)和足部溃疡的存在被确定为独立危险因素。500名参与者中有22名(4.4%)的ABI大于1.3,但在分析中被排除。

结论

通过ABI指数测量的糖尿病患者外周动脉疾病患病率较低,在我们的研究中,大多数患者患有轻度外周动脉疾病且无症状。ABI可用于糖尿病患者,但应根据临床情况精确解读其值,因为较高值很常见。