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一名儿童T系急性淋巴细胞白血病的骨复发

Bone relapse in T-lineage acute lymphoblastic leukemia in a child.

作者信息

Meena Jagdish Prasad, Ahad Abdul, Gupta Aditya Kumar, Mallick Saumyaranjan, Seth Rachna

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Oxf Med Case Reports. 2018 Sep 24;2018(10):omx110. doi: 10.1093/omcr/omx110. eCollection 2018 Oct.

Abstract

Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. T-cell ALL accounts for 10-15% of cases. ALL can rarely relapse in unusual extramedullary sites like bone. Hereby, we report a case of 7-year-old male child who was being treated for T-cell ALL and then presented with left arm swelling. This swelling was initially thought to be a bone tumor but later it was found to be infiltrated by leukemic blasts. We reviewed all previous cases and suggest that in a patient of ALL presenting with a bone swelling during or after completion of therapy, one should suspect of bone relapse.

摘要

急性淋巴细胞白血病(ALL)是儿童最常见的恶性肿瘤。T细胞ALL占病例的10%-15%。ALL很少在诸如骨骼等不寻常的髓外部位复发。在此,我们报告一例7岁男童,他正在接受T细胞ALL治疗,随后出现左臂肿胀。这种肿胀最初被认为是骨肿瘤,但后来发现是白血病原始细胞浸润。我们回顾了所有既往病例,并建议在ALL患者治疗期间或完成治疗后出现骨肿胀时,应怀疑骨复发。

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