Chhagan Usha, Burns Jonathan K
Department of Psychiatry, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
S Afr J Psychiatr. 2017 Jun 1;23:1050. doi: 10.4102/sajpsychiatry.v23i0.1050. eCollection 2017.
The use of neuroimaging modalities in psychiatry has been evaluated in several studies. The vast majority seem to suggest that neuroimaging may be overutilised in psychiatry. There is a significant constraint on availability and cost related to neuroimaging of patients at general state medical facilities. The routine use of computerised tomography (CT) scanning is thus questioned.
A retrospective analysis was undertaken of all psychiatric inpatients who had CT scans performed from 01 January 2011 to 31 December 2012. Demographic data, mental state examination, physical examination findings, substance use and diagnosis upon admission were recorded. The relationship between these variables and CT scan findings was analysed.
A total of 897 admissions were retrospectively analysed. One hundred and three patients had documented CT scan imaging. In total, 17 of the 23 patients with abnormal findings on CT scan were found to be psychotic (74.0%). The remaining 26.0% included depression and dementia. There was no statistically significant difference between the normal and abnormal CT scan groups with regard to gender, age, family history, substance use and physical examination. The majority (65.2%) had cerebral atrophy and/or cerebral calcifications. A smaller group of other documented findings was noted.
Selective indications and clinical markers may be utilised in order to justify brain imaging studies rather than performing them routinely. That being true, a multicentre study with a larger sample size is indicated to further improve the statistical significance and assist in formulating a more concrete guideline for neuroimaging of psychiatric patients.
多项研究对精神科中神经影像学检查手段的应用进行了评估。绝大多数研究似乎表明,神经影像学检查在精神科可能存在过度使用的情况。对于普通公立医疗机构的患者而言,神经影像学检查在可及性和成本方面存在显著限制。因此,计算机断层扫描(CT)的常规使用受到质疑。
对2011年1月1日至2012年12月31日期间接受CT扫描的所有精神科住院患者进行回顾性分析。记录人口统计学数据、精神状态检查、体格检查结果、物质使用情况及入院诊断。分析这些变量与CT扫描结果之间的关系。
共对897例入院病例进行了回顾性分析。其中103例患者有CT扫描影像记录。在CT扫描结果异常的23例患者中,共有17例被诊断为精神病性障碍(74.0%)。其余26.0%包括抑郁症和痴呆症。在性别、年龄、家族史、物质使用情况和体格检查方面,CT扫描正常组与异常组之间无统计学显著差异。大多数患者(65.2%)有脑萎缩和/或脑钙化。还记录了一小部分其他检查结果。
为证明脑部影像学检查的合理性,可使用选择性指征和临床标志物,而非进行常规检查。鉴于此,需要开展一项样本量更大的多中心研究,以进一步提高统计显著性,并协助制定更具体的精神科患者神经影像学检查指南。