Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
Department of Psychiatry and Human Behavior, Brown University, Coro Building, Suite 309, 164 Summit Ave, Providence, RI, 02906, USA.
AIDS Behav. 2019 May;23(5):1297-1305. doi: 10.1007/s10461-018-2278-z.
Despite advances in HIV antiretroviral medications, some patients do not achieve adequate medication adherence or suppressed viral load. The aim of this study was to identify the relationship between factors of impulsivity and medication non-adherence. It was hypothesized that impulsivity would have a direct association with non-adherence, after accounting for other known correlates. Participants included 322 HIV positive individuals (M age = 49, 56% male, 64% Black/African American). Impulsivity was measured using the Barratt Impulsiveness Scale-Brief (BIS-Brief). Factor analysis was conducted to determine if BIS-Brief resulted in a unidimensional or multi-factor solution. Results were suggestive of a two-factor solution: behavioral impulsivity and non-planning impulsivity. Structural equation modeling found non-planning impulsivity was associated with non-adherence (β = 0.18, p = 0.016), while no significant association was observed for behavioral impulsiveness. Results suggest that strategies related to planning for future consequences may be beneficial for impulsive persons with medication adherence difficulties.
尽管在 HIV 抗逆转录病毒药物方面取得了进展，但一些患者仍无法实现充分的药物依从性或抑制病毒载量。本研究旨在确定冲动因素与药物不依从之间的关系。研究假设，在考虑其他已知相关因素后，冲动性与不依从性之间存在直接关联。参与者包括 322 名 HIV 阳性个体（M 年龄=49 岁，56%为男性，64%为黑人/非裔美国人）。使用巴雷特冲动量表-简短版（BIS-Brief）测量冲动性。进行因子分析以确定 BIS-Brief 是否得出单维或多维解决方案。结果表明存在双因素解决方案：行为冲动性和非计划性冲动性。结构方程模型发现，非计划性冲动性与不依从相关（β=0.18，p=0.016），而行为冲动性则没有观察到显著关联。结果表明，与规划未来后果相关的策略可能对有药物依从性困难的冲动性个体有益。
