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抗生素骨水泥涂层髓内钉联合环形固定保肢治疗严重畸形、感染、神经关节病性踝关节

Combined Intramedullary Nail Coated With Antibiotic-Containing Cement and Ring Fixation for Limb Salvage in the Severely Deformed, Infected, Neuroarthropathic Ankle.

机构信息

1 Summit Orthopaedics, Portland, OR, USA.

2 Legacy Institute for Surgical Education & Innovation, Legacy Research Institute, Portland, OR, USA.

出版信息

Foot Ankle Int. 2019 Jan;40(1):48-55. doi: 10.1177/1071100718800836. Epub 2018 Sep 28.

Abstract

BACKGROUND

: The severely deformed, infected, and unstable neuroarthropathic ankle is challenging to treat. We evaluated our preliminary experience and results of combined internal and external ring fixation for a complex neuropathic population.

METHODS

: We retrospectively reviewed medical records and radiographs for 8 patients with unilateral severely deformed ankle neuroarthropathy associated with infection and ulceration. Treatment included single-stage reconstruction arthrodesis with an interlocked intramedullary nail coated with antibiotic-containing cement combined with ring fixation. Taylor Spatial Frame™ technology was used when the deformity was not amenable to acute correction (5 patients). Protected postoperative weightbearing was permitted. Their mean age averaged 55.6 (range, 42-66) years with an average body mass index of 38.4 (range, 28.7-49.6) kg/m.

RESULTS

: Seven patients achieved limb preservation. Average time for fusion healing was 15.2 (range, 12.2-22.2) weeks, frame time was 17.7 (range, 12.2-23.0) weeks, and follow-up was 34.1 (range, 24.1-68.8) months. All presenting wounds and infection successfully resolved. Reinker and Carpenter scale was excellent for 2 patients, good for 2 patients, and fair for 3 patients. Foot and Ankle Ability Measure averaged 59.0% (range, 39.3%-87.5%). One patient developed a recalcitrant calcaneal ulcer with osteomyelitis that required a transtibial amputation 17 months after successful ankle arthrodesis.

CONCLUSIONS

: Combined use of interlocked intramedullary nail and ring external fixation for neuroarthropathic ankle arthrodesis achieved a functional and clinically stable salvaged lower limb for most patients.

LEVEL OF EVIDENCE

: Level IV, retrospective case series.

摘要

背景

严重畸形、感染和不稳定的神经关节病踝关节治疗具有挑战性。我们评估了联合应用内、外固定环治疗复杂神经病变患者的初步经验和结果。

方法

我们回顾性分析了 8 例单侧严重畸形踝关节神经关节病合并感染和溃疡的患者的病历和影像学资料。治疗包括一期重建关节融合,使用带抗生素骨水泥涂层的交锁髓内钉,结合环形固定。当畸形不适合急性矫正时(5 例),使用 Taylor Spatial Frame™技术。允许术后保护性负重。患者平均年龄为 55.6 岁(范围,42-66 岁),平均体重指数为 38.4kg/m²(范围,28.7-49.6kg/m²)。

结果

7 例患者实现了肢体保留。融合愈合的平均时间为 15.2 周(范围,12.2-22.2 周),外固定架时间为 17.7 周(范围,12.2-23.0 周),随访时间为 34.1 个月(范围,24.1-68.8 个月)。所有的伤口和感染均得到成功治愈。Reinker 和 Carpenter 量表评分为优 2 例,良 2 例,可 3 例。足踝能力测量评分为 59.0%(范围,39.3%-87.5%)。1 例患者在成功踝关节融合后 17 个月出现难治性跟骨溃疡伴骨髓炎,需要进行胫骨截肢。

结论

联合应用交锁髓内钉和环形外固定架治疗神经关节病踝关节融合术,为大多数患者获得了功能和临床稳定的可挽救的下肢。

证据水平

IV 级,回顾性病例系列研究。

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