Department of Pediatrics, Johns Hopkins School of Medicine, 600 North Wolfe Street, CMSC 2-117, Baltimore, MD 21287, USA.
Department of Pediatrics, Johns Hopkins School of Medicine, 600 North Wolfe Street, CMSC 2-117, Baltimore, MD 21287, USA.
Clin Liver Dis. 2018 Nov;22(4):753-772. doi: 10.1016/j.cld.2018.06.008. Epub 2018 Aug 24.
Although liver tumors are rare in the pediatric population, they are common in the setting of children with specific risk factors requiring increased awareness and, in some instances, screening. The evaluation of a liver mass in children is largely driven by the age at diagnosis, the presence of any medical comorbidities, and initial testing with alpha fetoprotein and imaging. Specific guidelines for the management of different tumors have been implemented in recent years such that a multidisciplinary approach is ideal and care should be provided by centers with experience in their management.
虽然肝脏肿瘤在儿科人群中较为罕见,但在某些特定风险因素的儿童中较为常见,需要提高认识,在某些情况下还需要进行筛查。儿童肝脏肿块的评估主要取决于诊断时的年龄、是否存在任何合并症以及甲胎蛋白和影像学的初始检查。近年来已经实施了针对不同肿瘤的具体管理指南,因此多学科方法是理想的,并且应该由在其管理方面具有经验的中心提供治疗。