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[家族性息肉病和加德纳综合征中小肠腺瘤与癌——文献综述分析]

[Adenomas and carcinomas of the small intestine in familial polyposis and Gardner syndrome--analysis of a literature survey].

作者信息

Sellner F

出版信息

Dtsch Z Verdau Stoffwechselkr. 1986;46(5):287-93.

PMID:3026772
Abstract

An analysis of 70 case records from the literature of patients with familial polyposis or Gardner syndrome and adenomas or carcinomas of the small bowel demonstrated that there is no difference between the neoplasms of the small bowel in familial polyposis or in Gardner syndrome. Between the adenomas and the carcinomas of the small bowel it was possible to show, that there exists a similar close relation as in the large intestine. In some carcinomas of the small bowel rests of adenomas can be observed. The peak incidence of small bowel adenomas is more than a decade earlier than that of carcinomas. The distribution of adenomas in the small bowel is quite similar to that of carcinomas. Therefore it can be supposed, that the significance of familial polyposis coli and Gardner syndrome for the importance of an adenoma-carcinoma-sequence in the large bowel is also existing in the small bowel.

摘要

对70例家族性腺瘤性息肉病或加德纳综合征患者以及小肠腺瘤或癌患者的文献病例记录进行分析表明,家族性腺瘤性息肉病或加德纳综合征患者的小肠肿瘤之间没有差异。在小肠腺瘤和癌之间,可以证明存在与大肠中类似的密切关系。在一些小肠癌中可以观察到腺瘤残留。小肠腺瘤的发病高峰比癌早十多年。小肠腺瘤的分布与癌非常相似。因此可以推测,家族性腺瘤性息肉病和加德纳综合征对大肠腺瘤-癌序列重要性的意义在小肠中也存在。

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