Department of Pharmacy, Abdul Wali Khan University Mardan, Khyber Pakhtunkhwa 23200, Pakistan.
G.B. Pant National Institute of Himalayan Environment and Sustainable Development, Kosi Katarmal, Almora, Uttarakhand, India.
J Ethnopharmacol. 2019 Jan 30;229:46-53. doi: 10.1016/j.jep.2018.09.031. Epub 2018 Sep 27.
The genus Vanda (Family: Orchidaceae) comprises about 73 species mainly distributed in Southeast Asia. Plants belonging to this genus are being used in the traditional medicine systems in Asian countries specially in India, Nepal, China and Bangladesh.
The aim of this work was to review the scientific work about medicinal orchids of the genus Vanda regarding their traditional uses, reported bioactive components, and pharmacological activities.
The information related to traditional uses, pharmacological activities, and bioactive compounds was systematically collected from the scientific literature databases including SciFinder, Scopus, PubMed and Google Scholar, published books and conference proceedings.
The literature survey revealed diverse traditional uses of different species of Vanda, mainly against indigestion, wounds, hepatitis, dyspepsia, bronchitis, piles, rheumatism, and bone fracture. However, only few of them are investigated scientifically for their chemical constituents and pharmacological activities. Bioactive compounds including eucomic acid derivatives, phenanthrene derivatives and other phenolic compounds are reported from Vanda species. Different extracts were so far evaluated for number of pharmacological activities including neuroprotective, anti-aging, antimicrobial, anti-inflammatory, antioxidant, membrane stabilizing, wound healing and hepato-protective activities.
Vanda spp. are of much significance as ornamental flowers, but also used widely in traditional medicines and have potential for their diverse pharmacological activities. However, many members of the genus Vanda need further detailed studies regarding chemical constituents and mechanism-based pharmacological activities. Similarly, further studies should also focus on the conservation, cultivation and sustainable utilization of these species.
万代兰属（兰科）约有 73 个种，主要分布在东南亚。该属植物在亚洲国家的传统医学体系中被使用，特别是在印度、尼泊尔、中国和孟加拉国。
本工作旨在综述有关万代兰属药用兰花的科学研究，包括其传统用途、报道的生物活性成分和药理学活性。
从 SciFinder、Scopus、PubMed 和 Google Scholar 等科学文献数据库、出版书籍和会议论文集中系统收集有关传统用途、药理学活性和生物活性化合物的信息。
文献调查显示，不同种的万代兰具有多种传统用途，主要用于消化不良、伤口、肝炎、消化不良、支气管炎、痔疮、风湿病和骨折。然而，只有少数几种在化学组成和药理学活性方面进行了科学研究。从万代兰物种中报告了包括 eucomic 酸衍生物、菲衍生物和其他酚类化合物在内的生物活性化合物。不同的提取物迄今已被评估用于多种药理学活性，包括神经保护、抗老化、抗菌、抗炎、抗氧化、膜稳定、伤口愈合和保肝活性。
万代兰属不仅作为观赏花卉具有重要意义，而且在传统医学中也被广泛应用，并具有多种药理学活性的潜力。然而，该属的许多成员需要进一步详细研究其化学组成和基于机制的药理学活性。同样，进一步的研究也应侧重于这些物种的保护、栽培和可持续利用。
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