精神分裂症谱系障碍患者出院后一个月内每日用药依从性信念的时滞预测因素。
Time-lagged predictors of daily medication nonadherence beliefs during the month post-hospital discharge in patients with psychotic-spectrum disorders.
机构信息
Psychosocial Research Program, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA; Department of Psychiatry & Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Department of Psychology, Binghamton University (SUNY), Binghamton, NY, USA.
出版信息
Psychiatry Res. 2018 Dec;270:253-256. doi: 10.1016/j.psychres.2018.09.048. Epub 2018 Sep 21.
We used ecological momentary assessment (EMA) to examine the period following hospitalization when risk for medication nonadherence is highest among patients with psychotic-spectrum disorders. EMA data were collected daily via smartphones from 23 patients with psychotic-spectrum disorders (totaling 1149 surveys) in the month immediately following discharge. Nonadherence beliefs significantly correlated with percentage of medication doses. Time-lagged increases in irritability, sadness, life dissatisfaction, functional impairment, and previous day missed medication dose predicted subsequent increases in nonadherence beliefs over time. Future research should study mobile interventions that target the factors found to predict nonadherence beliefs to improve post-hospital recovery.
我们使用生态瞬时评估（EMA）来研究精神障碍患者住院后风险最高的药物不依从时期。通过智能手机，在出院后一个月内，从 23 名精神障碍患者（共 1149 份调查）中每天收集 EMA 数据。不依从信念与药物剂量百分比显著相关。愤怒、悲伤、生活不满、功能障碍和前一天漏服药物剂量的时间滞后增加预测了随后不依从信念的时间滞后增加。未来的研究应该研究针对预测不依从信念的因素的移动干预措施，以改善住院后的恢复。
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