Moitra Ethan, Gaudiano Brandon A, Davis Carter H, Ben-Zeev Dror
Warren Alpert Medical School of Brown University, Providence, RI 02912, USA.
Warren Alpert Medical School of Brown University, Providence, RI 02912, USA; Butler Hospital, Providence, RI 02906, USA.
Compr Psychiatry. 2017 Apr;74:204-213. doi: 10.1016/j.comppsych.2017.01.018. Epub 2017 Feb 7.
Up to 50% of patients with psychotic-spectrum disorders are medication nonadherent. The use of real-time assessment via ecological momentary assessment (EMA) on mobile devices might offer important insights into adherence behaviors that cannot be measured in the clinic. However, existing EMA studies have only studied acutely ill patients during hospitalization or more stable patients in the community.
Feasibility and acceptability of EMA in 65 patients with psychotic-spectrum disorders who were recently discharged from the hospital were assessed. EMA was administered for four weeks via study-provided mobile devices. Feasibility was measured by study recruitment/retention rates, patients' connectivity, and completion rates. Quantitative and qualitative acceptability data were collected.
Participants completed 28-31% of offered EMA assessments. The only significant predictor of reduced EMA completion was recent cannabis use. EMA completion was maintained from weeks 1 to 3 but significantly dropped at the fourth week. Patient acceptability feedback was generally positive; negative comments related primarily to technological problems.
This was the first study to use EMA in recently discharged patients with psychotic-spectrum disorders. EMA is feasible and acceptable in this population, but completion rates were lower than in more stable samples. Future research should consider limiting the assessment period, screening for substance use, and integrating assessment with intervention elements to increase EMA engagement.
高达50%的精神病谱系障碍患者不坚持服药。通过移动设备进行生态瞬时评估(EMA)的实时评估方法,可能为在诊所无法测量的服药依从行为提供重要见解。然而,现有的EMA研究仅针对住院期间的急性病患者或社区中病情较稳定的患者进行过研究。
对65名近期出院的精神病谱系障碍患者进行EMA的可行性和可接受性评估。通过研究提供的移动设备进行为期四周的EMA评估。可行性通过研究招募/保留率、患者的连接性和完成率来衡量。收集了定量和定性的可接受性数据。
参与者完成了所提供的EMA评估的28%-31%。EMA完成率降低的唯一显著预测因素是近期使用大麻。EMA完成率在第1至3周保持稳定,但在第4周显著下降。患者的可接受性反馈总体上是积极的;负面评论主要与技术问题有关。
这是第一项在近期出院的精神病谱系障碍患者中使用EMA的研究。EMA在该人群中是可行且可接受的,但完成率低于病情更稳定的样本。未来的研究应考虑限制评估期、筛查物质使用情况,并将评估与干预要素相结合,以提高EMA的参与度。