菲律宾巴科洛德市淋病奈瑟菌的抗生素敏感性监测
Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines.
作者信息
Araneta Clark Martin P, Juayang Alain C, Lim Joseph Peter T, Quilop Eleeza Marie G, Casaysay Nadine Joy G, Tamesis Gene Marie L, Yude Tricia Marie G, Romero Sarah Joyce E, Gayoba Raziel C
机构信息
Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines.
Pathology Department, Dr. Pablo O. Torre Memorial Hospital, Bacolod City 6100, Philippines.
出版信息
Trop Med Infect Dis. 2017 Aug 29;2(3):45. doi: 10.3390/tropicalmed2030045.
A local study was conducted to monitor the antibiotic susceptibility of in Bacolod City, Philippines. A total of 88 isolates were taken during the period of 1 January 2015 to 30 June 2017, from male patients ages 12 to 72 years. The highest incidence of gonorrhea infection was in the group aged 20⁻24 years (34.09%). The susceptibility pattern to antibiotics was as follows: ceftriaxone 100%, cefixime 82.6%, spectinomycin 92.1%, ciprofloxacin 4.9%, tetracycline 5.1%, and penicillin G with 0%. All isolates were noted to produce beta-lactamase, which can be attributed to plasmid-mediated penicillin resistance. These findings indicate that the resistance rates of to most commonly-used antibiotics are increasing, and that ceftriaxone remains an effective antibiotic in treating gonorrhea infections locally.
在菲律宾巴科洛德市开展了一项本地研究，以监测淋病奈瑟菌的抗生素敏感性。在2015年1月1日至2017年6月30日期间，共采集了88株分离株，来自年龄在12至72岁的男性患者。淋病感染发病率最高的是20 - 24岁年龄组（34.09%）。对抗生素的敏感性模式如下：头孢曲松100%、头孢克肟82.6%、壮观霉素92.1%、环丙沙星4.9%、四环素5.1%、青霉素G为0%。所有分离株均被发现产生β-内酰胺酶，这可归因于质粒介导的青霉素耐药性。这些发现表明，淋病奈瑟菌对最常用抗生素的耐药率正在上升，且头孢曲松在当地治疗淋病感染方面仍然是一种有效的抗生素。
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