Witt S N, Chan S I
J Biol Chem. 1987 Feb 5;262(4):1446-8.
Evidence is reported which shows that a reactive ferryl Fea3/cupric CuB binuclear couple is present at the dioxygen reduction site in "oxygenated" cytochrome c oxidase; when the fully reduced enzyme is reoxidized at low temperatures; and when partially reduced cytochrome c oxidase is reoxidized with dioxygen at room temperature.
有证据表明,在“氧化态”细胞色素c氧化酶的双氧还原位点存在一个反应性的高铁/铜双核对;当完全还原的酶在低温下再氧化时;以及当部分还原的细胞色素c氧化酶在室温下用双氧再氧化时。