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输卵管阻塞患者中子宫内膜息肉的患病率更高:一项病例对照研究。

Higher Prevalence of Endometrial Polyps in Patients with Fallopian Tube Obstruction: A Case-control Study.

机构信息

Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China (Drs. Sun and Bai).

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China (Dr. Zhang).

出版信息

J Minim Invasive Gynecol. 2019 Jul-Aug;26(5):935-940. doi: 10.1016/j.jmig.2018.07.024. Epub 2018 Sep 28.

DOI:10.1016/j.jmig.2018.07.024
PMID:30273685
Abstract

STUDY OBJECTIVE

To study the association between endometrial polyps and fallopian tube patency diagnosed by hysteroscopy, conventional histology, and 4-dimensional (4D) hysterosalpingo-contrast sonography (HyCoSy).

DESIGN

A case-control study (Canadian Task Force classification II-2).

SETTING

A university hospital.

PATIENTS

A total of 323 women of reproductive age underwent 4D HyCoSy and hysteroscopy between January 2015 and December 2017.

INTERVENTION

A retrospective analysis of the association of endometrial polyps and fallopian tube obstruction (n = 154) or patency (n = 169) in patients who underwent 4D HyCoSy.

MEASUREMENTS AND MAIN RESULTS

The prevalence of endometrial polyps was significantly higher in patients with bilateral fallopian tube obstruction than in patients with bilateral fallopian tube patency (42.9% [66/154] vs 20.1% [34/169], p <.0001). In univariate and multivariate analyses, the presence of endometrial polyps was found to be a risk factor for tubal obstruction with an odds ratio of 3.16 and 2.59, respectively.

CONCLUSION

The prevalence of endometrial polyps is higher in infertile patients with fallopian tube obstruction than in patients with fallopian tube patency. History of endometrial polyps, ectopic pregnancy, and pelvic inflammatory disease are risk factors for tubal obstruction.

摘要

研究目的

研究宫腔镜、常规组织学和 4 维(4D)子宫输卵管造影超声检查(HyCoSy)诊断的子宫内膜息肉与输卵管通畅性之间的关系。

设计

病例对照研究(加拿大任务组分类 II-2)。

设置

一所大学医院。

患者

2015 年 1 月至 2017 年 12 月,共有 323 名育龄妇女接受了 4D HyCoSy 和宫腔镜检查。

干预措施

回顾性分析 4D HyCoSy 检查中子宫内膜息肉与输卵管阻塞(n=154)或通畅(n=169)患者的相关性。

测量和主要结果

双侧输卵管阻塞患者中子宫内膜息肉的患病率明显高于双侧输卵管通畅患者(42.9%[66/154]vs 20.1%[34/169],p<0.0001)。在单因素和多因素分析中,存在子宫内膜息肉被发现是输卵管阻塞的危险因素,优势比分别为 3.16 和 2.59。

结论

在输卵管阻塞的不孕患者中,子宫内膜息肉的患病率高于输卵管通畅的患者。子宫内膜息肉病史、异位妊娠和盆腔炎是输卵管阻塞的危险因素。

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