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四维子宫输卵管造影检查后输卵管不完全阻塞患者应用通管抗炎药物的安全性和有效性评价。

Evaluation of the safety and effectiveness of tubal inflammatory drugs in patients with incomplete tubal obstruction after four-dimensional hysterosalpingo-contrast-sonography examination.

机构信息

Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Army Medical University, Chongqing, 400037, PR China.

Department of Radiology, the Second Affiliated Hospital of Army Medical University, Chongqing, 400037, PR China.

出版信息

BMC Pregnancy Childbirth. 2022 May 7;22(1):395. doi: 10.1186/s12884-022-04722-y.

Abstract

BACKGROUND

To investigate the safety and effectiveness of tubal inflammatory drugs in patients with incomplete tubal obstruction of at least one side after four-dimensional hysterosalpingo-contrast-sonography (4D-HyCoSy) examination.

METHODS

Two hundred fifteen cases of tubal incomplete obstruction were diagnosed by ultrasonography from February 2019 to November 2020.According to retrospective analysis,the patients in this study were divided into experimental and control groups; the experimental group combined with salpingitis drugs, and the control group received blank control. Basic information, degree of pain, postoperative complications, and pregnancy rate were then compared between the two groups.

RESULTS

Compared with the control group, there was no significant difference in the basic information; in preoperative, intraoperative, or postoperative pain; or in postoperative complications (P > 0.05). The cumulative pregnancy rate of the experimental group (26.8%) was statistically different from that of the control group (14.4%) (P < 0.05).

CONCLUSIONS

We observed that for infertile patients with incomplete obstruction of at least one fallopian tube as diagnosed by contrast-enhanced ultrasonography, salpingitis-treatment drugs effectively improved the pregnancy rate postoperatively, with high effectiveness and safety. This regimen is thus worthy of further investigation and promotion in the future.

摘要

背景

为了探讨在四维子宫输卵管造影(4D-HyCoSy)检查后至少一侧输卵管不完全阻塞的患者使用输卵管炎性药物的安全性和有效性。

方法

2019 年 2 月至 2020 年 11 月,通过超声诊断出 215 例输卵管不完全阻塞病例。根据回顾性分析,本研究将患者分为实验组和对照组;实验组结合输卵管炎药物治疗,对照组给予空白对照。然后比较两组的基本信息、疼痛程度、术后并发症和妊娠率。

结果

与对照组相比,两组的基本信息、术前、术中或术后疼痛或术后并发症均无统计学差异(P>0.05)。实验组(26.8%)的累积妊娠率与对照组(14.4%)有统计学差异(P<0.05)。

结论

我们观察到,对于通过增强超声检查诊断为至少一侧输卵管不完全阻塞的不孕患者,输卵管炎治疗药物可有效提高术后妊娠率,具有较高的有效性和安全性。因此,该方案值得在未来进一步研究和推广。

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