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采用两种 3D 打印技术制备的 Ti-6Al-4V 合金的腐蚀行为和细胞相互作用。

Corrosion behaviour and cell interaction of Ti-6Al-4V alloy prepared by two techniques of 3D printing.

机构信息

University of Chemistry and Technology, Prague, Department of Metals and Corrosion Engineering, Technicka 5, 166 28 Prague, Czech Republic.

University of Chemistry and Technology, Prague, Department of Metals and Corrosion Engineering, Technicka 5, 166 28 Prague, Czech Republic.

出版信息

Mater Sci Eng C Mater Biol Appl. 2018 Dec 1;93:911-920. doi: 10.1016/j.msec.2018.08.066. Epub 2018 Aug 31.

DOI:10.1016/j.msec.2018.08.066
PMID:30274128
Abstract

3D printing seems to be the technology of the future for the preparation of metallic implants. For such applications, corrosion behaviour is pivotal. However, little is published on this topic and with inconsistent results. Therefore, we carried out a complex study in which we compared two techniques of the 3D printing technology - selective laser melting and electron beam melting. The corrosion behaviour was studied in physiological solution by standard electrochemical techniques and susceptibility to localised corrosion was estimated too. All samples showed typical passive behaviour. Localised corrosion was shown to be possible on the original as-printed surfaces. Corrosion experiments were repeated tree times. To reveal possible negative effects of 3D printing on cytocompatibility, direct in vitro tests were performed with U-2 OS cells. The cells showed good viability and proliferation, but their growth was impeded by surface unevenness. Our results suggest that both techniques are suitable for implants production. Statistical evaluation was performed by ANOVA followed by Tukey's test.

摘要

3D 打印似乎是制备金属植入物的未来技术。对于此类应用,腐蚀行为至关重要。然而,关于这个主题的出版物很少,而且结果也不一致。因此,我们进行了一项复杂的研究,比较了 3D 打印技术的两种技术——选择性激光熔化和电子束熔化。通过标准电化学技术研究了腐蚀行为,并评估了局部腐蚀的敏感性。所有样品均表现出典型的钝化行为。在原始的打印表面上可能会出现局部腐蚀。腐蚀实验重复了三次。为了揭示 3D 打印对细胞相容性的可能负面影响,我们用 U-2 OS 细胞进行了直接的体外测试。这些细胞表现出良好的活力和增殖能力,但由于表面不平整,它们的生长受到了阻碍。我们的结果表明,这两种技术都适用于植入物的生产。统计评估通过方差分析和 Tukey 检验进行。

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