Hardstone Yoshimizu Melissa, Billeter Sarah A
Vector-Borne Disease Section, California Department of Public Health, 850 Marina Bay Parkway, Richmond, CA 94804, USA.
Vector-Borne Disease Section, California Department of Public Health, 2151 Convention Center Way Suite 218B, Ontario, CA 91764, USA.
Trop Med Infect Dis. 2018 Jan 3;3(1):2. doi: 10.3390/tropicalmed3010002.
The identification of pathogenic rickettsial agents has expanded over the last two decades. In North America, the majority of human cases are caused by tick-borne rickettsioses but rickettsiae transmitted by lice, fleas, mites and other arthropods are also responsible for clinical disease. Symptoms are generally nonspecific or mimic other infectious diseases; therefore, diagnosis and treatment may be delayed. While infection with most rickettsioses is relatively mild, delayed diagnosis and treatment may lead to increased morbidity and mortality. This review will discuss the ecology, epidemiology and public health importance of suspected and confirmed vector-transmitted species of North America associated with human diseases.
在过去二十年中，致病性立克次体病原体的识别范围有所扩大。在北美，大多数人类病例是由蜱传播的立克次体病引起的，但由虱子、跳蚤、螨虫和其他节肢动物传播的立克次体也会导致临床疾病。症状通常不具有特异性，或与其他传染病相似；因此，诊断和治疗可能会延迟。虽然大多数立克次体病感染相对较轻，但延迟诊断和治疗可能会导致发病率和死亡率上升。本综述将讨论与人类疾病相关的北美疑似和确诊的媒介传播物种的生态学、流行病学及公共卫生重要性。
