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名称的含义:在儿童精神药理学中采用基于神经科学的命名法。

What's in a Name? Moving to Neuroscience-Based Nomenclature in Pediatric Psychopharmacology.

机构信息

Columbia University and the New York State Psychiatric Institute, NY.

The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY; Hofstra Northwell School of Medicine, Hempstead, NY; Feinstein Institute for Medical Research, Manhasset, NY; Charité Universitätsmedizin, Berlin, Germany.

出版信息

J Am Acad Child Adolesc Psychiatry. 2018 Oct;57(10):719-721. doi: 10.1016/j.jaac.2018.05.024.

DOI:10.1016/j.jaac.2018.05.024
PMID:30274643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6428589/
Abstract

Our traditional names for psychotropic medication classes lead to unnecessary confusion. As clinicians, we have grown comfortable with idiosyncratic names of psychotropic medications and have forgotten how unclear and misleading they can be. For example, evidence shows that serotonin reuptake inhibitors help in pediatric anxiety disorders, but a parent with an anxious child might ask, "If you diagnosed my son with separation anxiety, why are you giving him an antidepressant?" Another parent might object to the use of a "stimulant" medication, "My daughter never slows down, the last thing she needs is a stimulant!" Similarly, an "antipsychotic" can be prescribed on-label to youth with mania, bipolar depression, tics, or irritability in autism but families and patients might be confused by or object to the implied label of being "psychotic." Furthermore, patients or family members may not feel comfortable asking clarifying questions and simply do not return for follow up-concluding that the provider does not understand their child.

摘要

我们对精神类药物类别的传统称谓会导致不必要的混淆。作为临床医生,我们已经习惯了精神类药物的特殊名称,但却忘记了它们可能是多么模糊和具有误导性。例如,有证据表明,5-羟色胺再摄取抑制剂有助于治疗儿童焦虑症,但有焦虑症孩子的父母可能会问:“如果您诊断我儿子患有分离焦虑症,为什么要给他开抗抑郁药?”另一位家长可能会反对使用“兴奋剂”药物,“我女儿从不慢下来,她最不需要的就是兴奋剂!”同样,一种“抗精神病药”可以在标签内用于治疗躁狂症、双相情感障碍、抽动症或自闭症中的易怒,但家庭和患者可能会对隐含的“精神病”标签感到困惑或反对。此外,患者或家属可能不会提出澄清问题,也不会回来进行随访,最终得出提供者不了解他们孩子的结论。

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本文引用的文献

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Efficacy and Safety of Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, and Placebo for Common Psychiatric Disorders Among Children and Adolescents: A Systematic Review and Meta-analysis.选择性5-羟色胺再摄取抑制剂、5-羟色胺-去甲肾上腺素再摄取抑制剂及安慰剂治疗儿童和青少年常见精神障碍的疗效与安全性:一项系统评价和荟萃分析
JAMA Psychiatry. 2017 Oct 1;74(10):1011-1020. doi: 10.1001/jamapsychiatry.2017.2432.
2
Update on the Use of SSRIs and SNRIs with Children and Adolescents in Clinical Practice.临床实践中5-羟色胺再摄取抑制剂(SSRI)和5-羟色胺去甲肾上腺素再摄取抑制剂(SNRI)在儿童及青少年中的应用进展
J Can Acad Child Adolesc Psychiatry. 2016 Winter;25(1):4-10. Epub 2016 Feb 1.
3
Lithium in Medicine: Mechanisms of Action.医学中的锂:作用机制
Met Ions Life Sci. 2016;16:557-84. doi: 10.1007/978-3-319-21756-7_15.
4
A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature.精神药物当前命名法综述及基于神经科学的命名法介绍。
Eur Neuropsychopharmacol. 2015 Dec;25(12):2318-25. doi: 10.1016/j.euroneuro.2015.08.019. Epub 2015 Sep 7.
5
Developments in pediatric psychopharmacology: focus on stimulants, antidepressants, and antipsychotics.儿科精神药理学的发展:重点关注兴奋剂、抗抑郁药和抗精神病药。
J Clin Psychiatry. 2011 May;72(5):655-70. doi: 10.4088/JCP.11r07064.