Eckburg Alexandra, Kazemi Tiana, Maguiness Sheilagh
University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Department of Dermatology, University of Minnesota, Minneapolis, Minnesota, USA.
Pediatr Dermatol. 2022 May;39(3):429-431. doi: 10.1111/pde.14963. Epub 2022 Mar 1.
Keratosis pilaris rubra (KPR) is a subtype of keratosis pilaris (KP) presenting with numerous "grainlike" follicular papules in a background of confluent erythema most often affecting the face and upper extremities with persistence beyond puberty. Treatment has remained challenging with inconsistent benefit from topical therapies such as emollients, keratolytics, corticosteroids, and retinoids, though case reports documenting success with pulsed dye laser therapy have been found. We present a case of KPR in a 15-year-old boy who was successfully treated with topical sirolimus 1% cream.
红色毛发角化病（KPR）是毛发角化病（KP）的一种亚型，表现为在融合性红斑背景下有许多“颗粒状”毛囊丘疹，最常累及面部和上肢，且持续至青春期后。尽管有文献记载脉冲染料激光治疗取得成功的病例报告，但外用疗法如润肤剂、角质剥脱剂、皮质类固醇和维甲酸类药物的疗效并不一致，治疗仍然具有挑战性。我们报告一例15岁男孩的KPR病例，该病例用1%西罗莫司外用乳膏成功治疗。
