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72例咽旁间隙肿瘤的分析与外科治疗

[Analysis and surgical treatment of 72 cases of parapharyngeal space tumors].

作者信息

Wen F, Shen H, Gao W H, wANG Q G, Qin Y, Xiao S F

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Peking University,Beijing,100034,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Sep;32(17):1343-1347. doi: 10.13201/j.issn.1001-1781.2018.17.012.

Abstract

To summarize and analyze the clinical features, diagnosis methods, surgical approaches and treatment outcomes of patients with parapharygeal space tumors.A retrospective review of 72 cases with parapharygeal space tumors treated from March 1994 to June 2017 was performed. The data on presentation, surgical approach, histological diagnosis and postoperative complications were reviewed.The postoperative pathological diagnosis included 62 benign tumors and 10 malignant tumors. The most frequent symptom was a cervical mass or an intraoral swelling. All patients underwent preoperative enhanced CT scan or MRI,which would be helpful to evaluate the tumor sizes,locations and possible sources,and to make operation scheme. The postoperative pathology included 24 salivary gland lesions and 30 neurogenic lesions. The postoperative complications happened in 13 patients. The surgical approaches included trans-cervical approach in 55 cases, cervical-parotid approach in 9 cases,trans-oral approach in 6 cases , and trans skull base approach in 2 case.A parapharygeal space tumor is an uncommon tumor and requires careful preoperative assessment. Surgery is the first choice for parapharygeal space tumors. These patients should be counseled appropriately about the potential for permanent cranial nerve deficits.

摘要

总结并分析咽旁间隙肿瘤患者的临床特征、诊断方法、手术方式及治疗效果。对1994年3月至2017年6月期间收治的72例咽旁间隙肿瘤患者进行回顾性研究。回顾患者的临床表现、手术方式、组织学诊断及术后并发症等资料。术后病理诊断包括62例良性肿瘤和10例恶性肿瘤。最常见的症状是颈部肿块或口内肿物。所有患者术前行增强CT扫描或MRI检查,有助于评估肿瘤大小、位置及可能的来源,并制定手术方案。术后病理包括24例涎腺病变和30例神经源性病变。13例患者出现术后并发症。手术方式包括经颈入路55例、颈腮腺入路9例、经口入路6例及经颅底入路2例。咽旁间隙肿瘤是一种少见肿瘤,术前需仔细评估。手术是咽旁间隙肿瘤的首选治疗方法。应向这些患者充分说明存在永久性颅神经功能缺损的可能性。

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