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颅内动脉瘤血管内治疗的良好结局:泰国的一项单中心研究

Favorable Outcome of Endovascular Treatment for Intracranial Aneurysms: A Single-Center Study in Thailand.

作者信息

Withayasuk Pattarawit, Churojana Anchalee, Songsaeng Dittapong, Aurboonyawat Taweesak, Chankaew Ekawut

机构信息

Department of Radiology, Interventional Neuroradiology Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Department of Surgery, Neurosurgery Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Asian J Neurosurg. 2018 Jul-Sep;13(3):721-729. doi: 10.4103/ajns.AJNS_70_18.

Abstract

PURPOSE

The purpose of this study is to collect the information on patients with intracranial aneurysm (IA) receiving endovascular management in Siriraj Hospital, Mahidol University, Thailand.

MATERIALS AND METHODS

We retrospectively reviewed data from patients with IA who underwent endovascular treatment from January 1997 through July 2013. We collected patients' demographic data including age, sex, clinical presentations, and aneurysmal profiles, as well as endovascular treatment technique, complications, angiographic results, and regrowth rate. Treatment results included success rate, clinical findings during follow-up, and regrowth rate.

RESULTS

We reviewed data from 497 patients with 636 aneurysms (female:male ratio, 1.9:1; age range, 15-90 years; mean age, 59.18 years) and 69% presented with rupture. One hundred and twenty patients with 127 aneurysms received endovascular treatment. The most common location for endovascular treatment was the posterior communicating artery (15.8%), and endovascular techniques were used most often for posterior circulation and paraclinoid aneurysms. The success rate was approximately 99.2% with a 16.5% regrowth rate and no rebleeding. Regrowth rate did not correlate with immediate postoperative angiographic findings. We encountered 23 complications (18.1%); most commonly, intra-procedural rupture (7/23). Good outcomes occurred in approximately 95.9% of the patients.

CONCLUSIONS

The success rate for endovascular treatment was >90%. Regrowth rate and clinical outcomes were within standard limits. Posterior circulation and paraclinoid aneurysms were our main targets. We tended to use fewer devices and simpler techniques to secure ruptured IA; however, the regrowth rate was similar to that using device-assisted techniques in other studies. We found no significant factors affecting regrowth rate, including immediate posttreatment angiographic results.

摘要

目的

本研究旨在收集泰国玛希隆大学诗里拉吉医院接受血管内治疗的颅内动脉瘤(IA)患者的信息。

材料与方法

我们回顾性分析了1997年1月至2013年7月期间接受血管内治疗的IA患者的数据。我们收集了患者的人口统计学数据,包括年龄、性别、临床表现和动脉瘤特征,以及血管内治疗技术、并发症、血管造影结果和再生长率。治疗结果包括成功率、随访期间的临床发现和再生长率。

结果

我们回顾了497例患者636个动脉瘤的数据(女性与男性比例为1.9:1;年龄范围为15 - 90岁;平均年龄为59.18岁),69%的患者表现为动脉瘤破裂。120例患者的127个动脉瘤接受了血管内治疗。血管内治疗最常见的部位是后交通动脉(15.8%),血管内技术最常用于后循环和床突旁动脉瘤。成功率约为99.2%,再生长率为16.5%,无再出血情况。再生长率与术后即刻血管造影结果无关。我们遇到了23例并发症(18.1%);最常见的是术中破裂(7/23)。约95.9%的患者预后良好。

结论

血管内治疗的成功率超过90%。再生长率和临床结果在标准范围内。后循环和床突旁动脉瘤是我们的主要治疗目标。对于破裂的IA,我们倾向于使用更少的器械和更简单的技术来确保治疗;然而,再生长率与其他研究中使用器械辅助技术的情况相似。我们未发现影响再生长率的显著因素,包括治疗后即刻血管造影结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f11/6159055/b04c7c43aeb3/AJNS-13-721-g001.jpg

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