Pülhorn Heinke, Chandran Arun, Nahser Hans, Wilby Martin John, McMahon Catherine
Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, L9 7LJ, UK.
Department of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool, L9 7LJ, UK.
Asian J Neurosurg. 2018 Jul-Sep;13(3):854-857. doi: 10.4103/ajns.AJNS_328_16.
Idiopathic intracranial hypertension (IIH) is a disease of mainly unknown etiology. Latest theories as to the pathogenesis have postulated a final common pathway of cerebral venous hypertension secondary to venous outflow impairment leading to decreased cerebrospinal fluid absorption. We present the case of a 42-year-old female who was treated for several years for headache and for approximately 12 months for IIH until appropriate imaging showed a right-sided cervical dural arteriovenous fistula (AVF) at the level of C4. The patient's IIH symptoms resolved following surgical excision of the fistula. We suggest that the cranial venous outflow impairment secondary to the cervical AVF was responsible for intracranial hypertension and that complete investigation of IIH patients should include imaging of the neck vasculature.
特发性颅内高压(IIH)是一种病因主要不明的疾病。关于其发病机制的最新理论推测,最终的共同途径是继发于静脉流出道受损导致脑脊液吸收减少的脑静脉高压。我们报告一例42岁女性病例,该患者因头痛接受了数年治疗,因IIH接受了约12个月治疗,直到合适的影像学检查显示在C4水平存在右侧颈段硬脑膜动静脉瘘(AVF)。瘘管手术切除后,患者的IIH症状得到缓解。我们认为,颈段AVF继发的颅静脉流出道受损是颅内高压的原因,对IIH患者的全面检查应包括颈部血管系统的影像学检查。