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假性脑瘤导致的视力丧失。57例患者5至41年的随访及14例永久性严重视力丧失患者的概况。

Visual loss in pseudotumor cerebri. Follow-up of 57 patients from five to 41 years and a profile of 14 patients with permanent severe visual loss.

作者信息

Corbett J J, Savino P J, Thompson H S, Kansu T, Schatz N J, Orr L S, Hopson D

出版信息

Arch Neurol. 1982 Aug;39(8):461-74. doi: 10.1001/archneur.1982.00510200003001.

DOI:10.1001/archneur.1982.00510200003001
PMID:7103794
Abstract

The prognosis for vision in most patients with pseudotumor cerebri is excellent; however, visual loss, which is the only serious complication, may occur either early or late in the course of the disease. A group of 57 patients was followed up five to 41 years with visual fields, visual acuity, and fundus photographs. Blinding visual loss or severe visual impairment in one or both eyes occurred in 14 patients, and in seven patients, this occurred months to years after the initial symptoms. Systemic hypertension was a significant risk factor for visual loss in patients with pseudotumor cerebri, and blindness occurred in eight of 13 patients who were hypertensive. Despite suggestions that blind spot measurement is useful for following up patients with this condition, we believe that sequential quantitative perimetry gives more complete information and is essential to rational decision making in the treatment of pseudotumor cerebri.

摘要

大多数假性脑瘤患者的视力预后良好;然而,视力丧失作为唯一的严重并发症,可能在疾病过程的早期或晚期出现。一组57例患者接受了5至41年的随访,检查项目包括视野、视力和眼底照片。14例患者出现单眼或双眼致盲性视力丧失或严重视力损害,其中7例在出现初始症状数月至数年之后发生。系统性高血压是假性脑瘤患者视力丧失的一个重要危险因素,13例高血压患者中有8例失明。尽管有观点认为盲点测量对随访此类患者有用,但我们认为,连续定量视野检查能提供更完整的信息,对于假性脑瘤治疗的合理决策至关重要。

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