Chaudhary Ammad Javaid, Jamali Taher, Dababneh Yara, Saleem Abdulmalik, Salgia Reena
Internal Medicine Department, Henry Ford Hospital, Detroit, MI.
Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.
ACG Case Rep J. 2024 Aug 5;11(8):e01418. doi: 10.14309/crj.0000000000001418. eCollection 2024 Aug.
Our case highlights a rare instance of recurrent metastatic solid pseudopapillary epithelial neoplasms of the pancreas, emerging 8 years after radical pancreatic resection-an extended interval surpassing the reported average. Managing solid pseudopapillary epithelial neoplasm during pregnancy is uniquely challenging, given the increase in the expression of progesterone receptors during the intrapartum period, leading to tumor growth. Although surgical resection remains the primary approach, systemic chemotherapy, radiation therapy, and liver transplant are other considerations. The absence of consensus guidelines for recurrence monitoring emphasizes the need for vigilant, long-term surveillance extending beyond the conventional 5-year mark.
我们的病例突出显示了胰腺实性假乳头状上皮性肿瘤复发转移的罕见情况，在根治性胰腺切除术后8年出现，这一较长间隔超过了报道的平均时间。鉴于分娩期孕酮受体表达增加导致肿瘤生长，孕期处理实性假乳头状上皮性肿瘤极具挑战性。尽管手术切除仍是主要治疗方法，但全身化疗、放射治疗和肝移植也是其他可考虑的方案。目前缺乏关于复发监测的共识指南，这凸显了超越传统5年期限进行长期密切监测的必要性。
