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头颈部滑膜肉瘤

Synovial sarcoma of the head and neck.

作者信息

Moore D M, Berke G S

出版信息

Arch Otolaryngol Head Neck Surg. 1987 Mar;113(3):311-3. doi: 10.1001/archotol.1987.01860030087015.

DOI:10.1001/archotol.1987.01860030087015
PMID:3028451
Abstract

Synovial sarcoma, a malignant soft-tissue tumor that occurs primarily in the extremities, is seen rarely in the head and neck. Although known to behave aggressively in the extremities, recent reports suggest that the course of synovial sarcoma may be more indolent when it occurs in the head and neck. Five new cases of synovial sarcoma of the head and neck are described herein. Of four patients with adequate follow-up, three died of pulmonary metastases at 1, 2 1/2, and 8 years following initial treatment. The fourth patient is alive with disease at the primary site six years after diagnosis. The poor prognosis for patients with this disease suggests that aggressive treatment is necessary.

摘要

滑膜肉瘤是一种主要发生在四肢的恶性软组织肿瘤,在头颈部很少见。虽然已知其在四肢具有侵袭性,但最近的报告表明,滑膜肉瘤发生在头颈部时病程可能较为惰性。本文描述了5例新的头颈部滑膜肉瘤病例。在4例有充分随访的患者中,3例在初始治疗后1年、2年半和8年死于肺转移。第4例患者在诊断后6年,原发部位仍有疾病存活。这种疾病患者的预后较差,提示需要积极治疗。

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