Dolman P J, Rootman J, Dolman C L
Br J Ophthalmol. 1987 Jan;71(1):47-53. doi: 10.1136/bjo.71.1.47.
A surgical biopsy of an infiltrative retrobulbar mass in a 44-year-old man was diagnosed as granular cell tumour. Electron microscopy and immunoperoxidase stains were used to confirm the diagnosis and to study the histogenesis of this rare soft tissue neoplasm. S-100 stain was positive, while neuron-specific enolase and myoglobin stains were negative, suggesting a non-specific neural origin for the cells. The capability of this tumour to invade surrounding tissues has seldom been described in the orbit and is demonstrated by this case.
一名44岁男性眼眶后浸润性肿块的手术活检被诊断为颗粒细胞瘤。使用电子显微镜和免疫过氧化物酶染色来确诊并研究这种罕见软组织肿瘤的组织发生。S-100染色呈阳性,而神经元特异性烯醇化酶和肌红蛋白染色呈阴性,提示细胞起源于非特异性神经组织。该肿瘤侵犯周围组织的能力在眼眶中很少被描述,此病例证实了这一点。